Understanding the role of AMPA receptors in autism: insights from circuit and synapse dysfunction
A Jimenez-Gomez, MX Nguyen, JS Gill - Frontiers in Psychiatry, 2024 - frontiersin.org
Autism spectrum disorders represent a diverse etiological spectrum that converge on a
syndrome characterized by discrepant deficits in developmental domains often highlighted …
syndrome characterized by discrepant deficits in developmental domains often highlighted …
Autism patient-derived SHANK2BY29X mutation affects the development of ALDH1A1 negative dopamine neuron
W Lai, Y Zhao, Y Chen, Z Dai, R Chen, Y Niu… - Molecular …, 2024 - nature.com
Autism spectrum disorder (ASD) encompasses a range of neurodevelopmental conditions.
Different mutations on a single ASD gene contribute to heterogeneity of disease …
Different mutations on a single ASD gene contribute to heterogeneity of disease …
A roadmap for SHANK3-related Epilepsy Research: recommendations from the 2023 strategic planning workshop
MC Savage, G Bliss, JD Buxbaum… - … Advances in Rare …, 2024 - journals.sagepub.com
On September 27, 2023, the CureSHANK nonprofit foundation sponsored a conference in
Boston, Massachusetts, to identify gaps in knowledge surrounding SHANK3-related …
Boston, Massachusetts, to identify gaps in knowledge surrounding SHANK3-related …
Exosomes can modulate the early hyperexcitability in cortical neurons with ASD-associated Shank3 mutation.
Shank3, a scaffolding protein, is critical for synaptic structure and function, particularly for the
formation and maintenance of dendritic spines. Shank3 mutations are strongly implicated in …
formation and maintenance of dendritic spines. Shank3 mutations are strongly implicated in …