[HTML][HTML] An overview of biological macromolecule crystallization
The elucidation of the three dimensional structure of biological macromolecules has
provided an important contribution to our current understanding of many basic mechanisms …
provided an important contribution to our current understanding of many basic mechanisms …
A historical perspective on protein crystallization from 1840 to the present day
R Giegé - The FEBS journal, 2013 - Wiley Online Library
Protein crystallization has been known since 1840 and can prove to be straightforward but,
in most cases, it constitutes a real bottleneck. This stimulated the birth of the …
in most cases, it constitutes a real bottleneck. This stimulated the birth of the …
Crystallization of soluble proteins in vapor diffusion for x-ray crystallography
M Benvenuti, S Mangani - Nature protocols, 2007 - nature.com
The preparation of protein single crystals represents one of the major obstacles in obtaining
the detailed 3D structure of a biological macromolecule. The complete automation of the …
the detailed 3D structure of a biological macromolecule. The complete automation of the …
High throughput screening of crystallization of materials
High throughput screening of crystallization of a target material is accomplishcd by
simultancously introducing a solution of the target material into a plurality of chambers of a …
simultancously introducing a solution of the target material into a plurality of chambers of a …
Integrated chip carriers with thermocycler interfaces and methods of using the same
G Facer, R Grossman, M Unger, P Lam… - US Patent …, 2010 - Google Patents
(60) Provisional application No. 60/558.316, filed on Mar. mal control source. Reagents for
carrying out a desired reac 30, 2004, provisional application No. 60/557,715, tion are …
carrying out a desired reac 30, 2004, provisional application No. 60/557,715, tion are …
Strategies in making cross-linked enzyme crystals
J Jegan Roy, T Emilia Abraham - Chemical Reviews, 2004 - ACS Publications
Enzymes are recognized as useful tools for accomplishing industrially important chemical
reactions in stereo-, regio-, and chemoselective ways. Biocatalytic routes that have emerged …
reactions in stereo-, regio-, and chemoselective ways. Biocatalytic routes that have emerged …
Crystal growth devices and systems, and methods for using same
HR Nassef, G Facer, JW Barco - US Patent 7,279,146, 2007 - Google Patents
C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC
MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY …
MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY …
Integrated chip carriers with thermocycler interfaces and methods of using the same
G Facer, R Grossman, M Unger, P Lam… - US Patent …, 2011 - Google Patents
Methods and systems are provided for conducting a reaction at a selected temperature or
range of temperatures over time. An array device is provided. The array device contains …
range of temperatures over time. An array device is provided. The array device contains …
Microfluidic free interface diffusion techniques
A static fluid and a second fluid are placed into contact along a microfluidic free interface
and allowed to mix by diffusion without convective flow across the interface. In accordance …
and allowed to mix by diffusion without convective flow across the interface. In accordance …
Large-scale crystallization of proteins for purification and formulation
D Hekmat - Bioprocess and biosystems engineering, 2015 - Springer
Since about 170 years, salts were used to create supersaturated solutions and crystallize
proteins. The dehydrating effect of salts as well as their kosmotropic or chaotropic character …
proteins. The dehydrating effect of salts as well as their kosmotropic or chaotropic character …