Biological agents and the aging brain: glial inflammation and neurotoxic signaling
AS Latham, JA Moreno, CE Geer - Frontiers in Aging, 2023 - frontiersin.org
Neuroinflammation is a universal characteristic of brain aging and neurological disorders,
irrespective of the disease state. Glial inflammation mediates this signaling, through …
irrespective of the disease state. Glial inflammation mediates this signaling, through …
Deep analysis of CD4 T cells in the rhesus CNS during SIV infection
Virologic suppression with antiretroviral therapy (ART) has significantly improved health
outcomes for people living with HIV, yet challenges related to chronic inflammation in the …
outcomes for people living with HIV, yet challenges related to chronic inflammation in the …
Chronic SIV-Induced neuroinflammation disrupts CCR7+ CD4+ T cell immunosurveillance in the rhesus macaque brain
SR Elizaldi, CE Hawes, A Verma… - The Journal of …, 2024 - Am Soc Clin Investig
CD4+ T cells survey and maintain immune homeostasis in the brain, yet their differentiation
states and functional capabilities remain unclear. Our approach, combining single-cell …
states and functional capabilities remain unclear. Our approach, combining single-cell …
[HTML][HTML] Comprehensive transcriptomic analyses identify the immunosuppressive effects of LLDT-8 in ART-treated SIV-infected rhesus macaques
X Liu, T Lv, X Li, J Xue, L Lin, L Lu, X Li, Y Yang… - International …, 2024 - Elsevier
Background Chronic immune activation plays a significant role in the pathogenesis and
disease progression of human immunodeficiency virus (HIV), and the existing interventions …
disease progression of human immunodeficiency virus (HIV), and the existing interventions …
[HTML][HTML] CD4 T cell Responses in the CNS during SIV infection
Virologic suppression with antiretroviral therapy (ART) has significantly improved health
outcomes for people living with HIV, yet challenges related to chronic inflammation in the …
outcomes for people living with HIV, yet challenges related to chronic inflammation in the …
CCR7+ CD4 T Cell Immunosurveillance Disrupted in Chronic SIV-Induced Neuroinflammation in Rhesus Brain
ABSTRACT CD4 T cells survey and maintain immune homeostasis in the brain, yet their
differentiation states and functional capabilities remain unclear. Our approach, combining …
differentiation states and functional capabilities remain unclear. Our approach, combining …
Persistent Neuropathogenesis and the Role of Myeloid Extracellular Vesicles in a SHIV. D/Macaque Model of Human Immunodeficiency Virus
R Podgorski - 2024 - search.proquest.com
While the success of combination antiretroviral therapy (ART) has extended the lifespan of
people with human immunodeficiency virus (HIV)(PWH), approximately half of PWH on …
people with human immunodeficiency virus (HIV)(PWH), approximately half of PWH on …