HIV genetic diversity between plasma and cerebrospinal fluid in patients with HIV encephalitis

C Soulie, S Fourati, S Lambert-Niclot, R Tubiana… - Aids, 2010 - journals.lww.com
In patients with HIV encephalitis, a low viral diversity between the plasma and cerebrospinal
fluid (CSF) HIV-1 viruses was associated with detectable HIV RNA in plasma and a higher …

Emergence of CD4 independence envelopes and astrocyte infection in R5 simian-human immunodeficiency virus model of encephalitis

K Zhuang, AR Leda, L Tsai, H Knight… - Journal of …, 2014 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) infection in the central nervous system (CNS)
is characterized by replication in macrophages or brain microglia that express low levels of …

Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy

MF Kearney, EM Anderson, C Coomer, L Smith… - Retrovirology, 2015 - Springer
Background Determining the anatomic compartments that contribute to plasma HIV-1 is
critical to understanding the sources of residual viremia during combination antiretroviral …

HIV coreceptor tropism in paired plasma, peripheral blood mononuclear cell, and cerebrospinal fluid isolates from antiretroviral-naive subjects

SG Parisi, C Andreoni, L Sarmati… - Journal of clinical …, 2011 - Am Soc Microbiol
ABSTRACT A survey of HIV coreceptor usage in cerebrospinal fluid (CSF) samples,
peripheral blood mononuclear cells (PBMCs), and plasma samples from naïve seropositive …

Statistical Integration of 1H NMR and MRS Data from Different Biofluids and Tissues Enhances Recovery of Biological Information from Individuals with HIV-1 …

AD Maher, LA Cysique, BJ Brew… - Journal of proteome …, 2011 - ACS Publications
Nuclear magnetic resonance (NMR) spectroscopy is widely used in metabonomics studies,
but optimal recovery of latent biological information requires increasingly sophisticated …

HIV subtype is not associated with dementia among individuals with moderate and advanced immunosuppression in Kampala, Uganda

N Sacktor, N Nakasujja, AD Redd, J Manucci… - Metabolic brain …, 2014 - Springer
HIV-associated neurocognitive disorders (HAND) are a common neurological manifestation
of HIV infection. A previous study suggested that HIV dementia may be more common …

Monocyte and CD4+ T-cell antiviral and innate responses associated with HIV-1 inflammation and cognitive impairment

V Sharma, C Bryant, M Montero, M Creegan, B Slike… - Aids, 2020 - journals.lww.com
Objective: Mechanisms underlying immune activation and HIV-associated neurocognitive
disorders (HAND) in untreated chronic infection remain unclear. The objective of this study …

Cerebrospinal fluid analysis in the HIV infection and compartmentalization of HIV in the central nervous system

SM Almeida - Arquivos de neuro-psiquiatria, 2015 - SciELO Brasil
The nervous system plays an important role in HIV infection. The purpose of this review is to
discuss the indications for cerebrospinal fluid (CSF) analysis in HIV infection in clinical …

Dynamic of CSF and serum biomarkers in HIV-1 subtype C encephalitis with CNS genetic compartmentalization—case study

SM de Almeida, I Rotta, CE Ribeiro, MF Oliveira… - Journal of …, 2017 - Springer
Despite the effective suppression of viremia with antiretroviral therapy, HIV can still replicate
in the central nervous system (CNS). This was a longitudinal study of the cerebrospinal fluid …

Cerebrospinal fluid viral load across the spectrum of untreated HIV-1 infection: a cross-sectional multi-center study

G Ulfhammer, A Edén, A Antinori, BJ Brew… - Clinical Infectious …, 2021 - iris.unito.it
Background: The aim of this large multicenter study was to determine variations in
cerebrospinal fluid (CSF) HIV-RNA in different phases of untreated HIV-1 infection and its …