Models and theories in behaviour change science are not in short supply, but they almost
exclusively pertain to a particular facet of behaviour, such as automaticity or reasoned …

Hormone rhythms are ubiquitous and essential to sustain normal physiological functions.
Combined mathematical modelling and experimental approaches have shown that these …

Stress is an important risk factor for modern chronic diseases, with distinct influences in
males and females. The sex specificity of the mammalian stress response contributes to the …

Major depressive disorder (MDD) and obesity are dominant and inter-related health
burdens. Obesity is a risk factor for MDD, and there is evidence MDD increases risk of …

Coping flexibility, as defined by the dual-process theory, refers to one's ability to relinquish a
coping strategy recognized as ineffective—abandonment—and to devise and implement an …

Nervous system processes, including cognition and affective state, fundamentally rely on
mitochondria. Impaired mitochondrial function is evident in major depressive disorder …

Introduction Major depressive disorder (MDD) is a mental disorder caused by the
combination of genetic, environmental, and psychological factors. Over the years, a number …

Melatonin is a neurohormone that maintains the circadian rhythms of the body. By regulating
the secretion of other hormones and neurotransmitters, it acts as a pleiotropic modulator that …

Depression is associated with immune dysregulation and the aberrant activity of the
hypothalamic-pituitary-adrenal (HPA) axis. However, the neurobiological molecular …

Vascular cognitive impairment (VCI) and depression frequently coexist in geriatric
populations and reciprocally increase disease risks. We assert that a shared pre-disease …