Targeting epigenetics: A novel promise for Alzheimer's disease treatment
D Jeremic, L Jiménez-Díaz, JD Navarro-López - Ageing Research Reviews, 2023 - Elsevier
So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …
approved drugs attenuate some symptoms, but do not halt the progress of this disease …
Insights into role of microRNA in Alzheimer's disease: from contemporary research to bedside perspective
M Bandakinda, A Mishra - International Journal of Biological …, 2023 - Elsevier
One of the most prevalent neurodegenerative disorders is Alzheimer's disease (AD). Despite
the pervasiveness of AD being considerable, the rates of both diagnosis and therapy are …
the pervasiveness of AD being considerable, the rates of both diagnosis and therapy are …
Molecular mechanisms and therapeutic strategies for levodopa-induced dyskinesia in Parkinson's disease: a perspective through preclinical and clinical evidence
R Bandopadhyay, N Mishra, R Rana, G Kaur… - Frontiers in …, 2022 - frontiersin.org
Parkinson's disease (PD) is the second leading neurodegenerative disease that is
characterized by severe locomotor abnormalities. Levodopa (L-DOPA) treatment has been …
characterized by severe locomotor abnormalities. Levodopa (L-DOPA) treatment has been …
Neuroepigenetics of ageing and neurodegeneration-associated dementia: an updated review
Gene expression is tremendously altered in the brain during memory acquisition, recall, and
forgetfulness. However, non-genetic factors, including environmental elements, epigenetic …
forgetfulness. However, non-genetic factors, including environmental elements, epigenetic …
The Role of Hydrogen Sulfide (H2S) in Epigenetic Regulation of Neurodegenerative Diseases: A Systematic Review
BG Dogaru, C Munteanu - International Journal of Molecular Sciences, 2023 - mdpi.com
This review explores the emerging role of hydrogen sulfide (H2S) in modulating epigenetic
mechanisms involved in neurodegenerative diseases. Accumulating evidence has begun to …
mechanisms involved in neurodegenerative diseases. Accumulating evidence has begun to …
Dissecting the relationship between neuropsychiatric and neurodegenerative disorders
Neurodegenerative diseases (NDDs) and neuropsychiatric disorders (NPDs) are two
common causes of death in elderly people, which includes progressive neuronal cell death …
common causes of death in elderly people, which includes progressive neuronal cell death …
Epidrugs in the therapy of central nervous system disorders: a way to drive on?
MG Gladkova, E Leidmaa, EA Anderzhanova - Cells, 2023 - mdpi.com
The polygenic nature of neurological and psychiatric syndromes and the significant impact
of environmental factors on the underlying developmental, homeostatic, and neuroplastic …
of environmental factors on the underlying developmental, homeostatic, and neuroplastic …
Epigenome editing for targeted DNA (de) methylation: a new perspective in modulating gene expression
Traditionally, it has been believed that inheritance is driven as phenotypic variations
resulting from changes in DNA sequence. However, this paradigm has been challenged and …
resulting from changes in DNA sequence. However, this paradigm has been challenged and …
A multi-trait association analysis of brain disorders and platelet traits identifies novel susceptibility loci for major depression, Alzheimer's and Parkinson's disease
A Tirozzi, MS Quiccione, C Cerletti, MB Donati… - Cells, 2023 - mdpi.com
Among candidate neurodegenerative/neuropsychiatric risk-predictive biomarkers, platelet
count, mean platelet volume and platelet distribution width have been associated with the …
count, mean platelet volume and platelet distribution width have been associated with the …
[HTML][HTML] The role of DNA methylation in progression of neurological disorders and neurodegenerative diseases as well as the prospect of using DNA methylation …
Genome-wide studies related to neurological disorders and neurodegenerative diseases
have pointed to the role of epigenetic changes such as DNA methylation, histone …
have pointed to the role of epigenetic changes such as DNA methylation, histone …