Stem cell tracking in human trials: a meta-regression
The potential effectiveness of cell therapies is dependent upon homing of transplanted cells
to relevant target organs. In this study we firstly characterise the range of methods employed …
to relevant target organs. In this study we firstly characterise the range of methods employed …
Dendritic cell engineering for tumor immunotherapy: from biology to clinical translation
Dendritic cells (DCs) are the most potent APCs, with the ability to orchestrate a repertoire of
immune responses. DCs play a pivotal role in the initiation, programming and regulation of …
immune responses. DCs play a pivotal role in the initiation, programming and regulation of …
Role of fatty-acid synthesis in dendritic cell generation and function
Dendritic cells (DC) are professional APCs that regulate innate and adaptive immunity. The
role of fatty-acid synthesis in DC development and function is uncertain. We found that …
role of fatty-acid synthesis in DC development and function is uncertain. We found that …
Alginate-coated chitosan nanogel capacity to modulate the effect of TLR ligands on blood dendritic cells
T Démoulins, I Bassi, L Thomann-Harwood… - … , Biology and Medicine, 2013 - Elsevier
Biodegradable nanoparticles have been employed for vaccine delivery, frequently admixed
with adjuvants. Surprisingly, there is little information on their modulation of immune …
with adjuvants. Surprisingly, there is little information on their modulation of immune …
[HTML][HTML] Hepatocellular carcinoma-specific immunotherapy with synthesized α1, 3-galactosyl epitope-pulsed dendritic cells and cytokine-induced killer cells
Y Qiu, MB Xu, MM Yun, YZ Wang… - World Journal of …, 2011 - ncbi.nlm.nih.gov
AIM: To evaluate the safety and clinical efficacy of a new immunotherapy using both α-Gal
epitope-pulsed dendritic cells (DCs) and cytokine-induced killer cells. METHODS: Freshly …
epitope-pulsed dendritic cells (DCs) and cytokine-induced killer cells. METHODS: Freshly …
Temporary elimination of IL-10 enhanced the effectiveness of cyclophosphamide and BMDC-based therapy by decrease of the suppressor activity of MDSCs and …
J Rossowska, N Anger, J Kicielińska… - Immunobiology, 2015 - Elsevier
The antitumour activity of the dendritic cell (DC)-based cellular vaccines is greatly reduced
in hostile tumour microenvironment. Therefore, there are many attempts to eliminate or …
in hostile tumour microenvironment. Therefore, there are many attempts to eliminate or …
Leishmaniasis: focus on the design of nanoparticulate vaccine delivery systems
Although mass vaccination of the entire population of an endemic area would be the most
cost-effective tool to diminish Leishmania burden, an effective vaccine is not yet …
cost-effective tool to diminish Leishmania burden, an effective vaccine is not yet …
Tolerogenic dendritic cells inhibit antiphospholipid syndrome derived effector/memory CD4+ T cell response to β2GPI
H Torres-Aguilar, M Blank, S Kivity, M Misgav… - Annals of the …, 2012 - ard.bmj.com
Objectives The importance of β2-glycoprotein I (β2GPI)-specific CD4+ T cells in the
development of pathogenic processes in patients with antiphospholipid syndrome (APS) …
development of pathogenic processes in patients with antiphospholipid syndrome (APS) …
Cyclophosphamide and IL-12-transduced DCs Enhance the Antitumor Activity of Tumor Antigen–stimulated DCs and Reduce Tregs and MDSCs Number
J Rossowska, E Pajtasz-Piasecka, N Anger… - Journal of …, 2014 - journals.lww.com
A hostile tumor microenvironment, characterized by an abundance of T regulatory cells and
myeloid-derived suppressor cells (MDSCs), considerably limits the efficacy of dendritic cell …
myeloid-derived suppressor cells (MDSCs), considerably limits the efficacy of dendritic cell …
[HTML][HTML] Immunomodulatory potential of anticancer therapy composed of methotrexate nanoconjugate and dendritic cell‑based vaccines in murine colon carcinoma
A Szczygieł, N Anger‑Góra… - Oncology …, 2021 - spandidos-publications.com
Chemotherapy with low‑molecular weight compounds, despite elimination of cancer cells,
entails adverse effects. To overcome this disadvantage, innovative drug delivery systems …
entails adverse effects. To overcome this disadvantage, innovative drug delivery systems …