Green biomanufacturing in recombinant collagen biosynthesis: trends and selection in various expression systems

Z Zhao, J Deng, D Fan - Biomaterials Science, 2023 - pubs.rsc.org
Collagen, classically derived from animal tissue, is an all-important protein material widely
used in biomedical materials, cosmetics, fodder, food, etc. The production of recombinant …

Using oils and fats to replace sugars as feedstocks for biomanufacturing: challenges and opportunities for the yeast Yarrowia lipolytica

YHV Soong, SM Coleman, N Liu, J Qin, C Lawton… - Biotechnology …, 2023 - Elsevier
More than 200 million tons of plant oils and animal fats are produced annually worldwide
from oil, crops, and the rendered animal fat industry. Triacylglycerol, an abundant energy …

Metabolic engineering of Yarrowia Lipolytica for high-level production of squalene

Z Liu, M Huang, H Chen, X Lu, Y Tian, P Hu… - Bioresource …, 2024 - Elsevier
Squalene is an important triterpene with a wide range of applications. Given the growing
market demand for squalene, the development of microbial cell factories capable of …

Systematic metabolic engineering of Yarrowia lipolytica for the enhanced production of erythritol

S Yang, X Pan, J You, B Guo, Z Liu, Y Cao, G Li… - Bioresource …, 2024 - Elsevier
In recent times, there has been a growing interest in exploring microbial strains that exhibit
enhanced erythritol productivity. Nonetheless, the lack of advanced synthetic biology tools …

High titer production of gastrodin enabled by systematic refactoring of yeast genome and an antisense-transcriptional regulation toolkit

Y Gu, Y Jiang, C Li, J Zhu, X Lu, J Ge, M Hu, J Deng… - Metabolic …, 2024 - Elsevier
Gastrodin, a phenolic glycoside, is a prominent component of Gastrodia elata, which is
renowned for its sedative, hypnotic, anticonvulsant, and neuroprotective activities …

Research status of indole-modified natural products

SF Duan, L Song, HY Guo, H Deng, X Huang… - RSC Medicinal …, 2023 - pubs.rsc.org
Indole is a heterocyclic compound formed by the fusion of a benzene ring and pyrrole ring,
which has rich biological activity. Many indole-containing compounds have been sold on the …

Carotenoid cleavage dioxygenase 1 and its application for the production of C13-apocarotenoids in microbial cell factories: A review

Z Qi, X Tong, Y Zhang, S Jia, X Fang… - Journal of Agricultural …, 2023 - ACS Publications
C13-apocarotenoids are naturally derived from the C9–C10 (C9′–C10′) double-bond
cleavage of carotenoids by carotenoid cleavage dioxygenases (CCDs). As high-value …

Metabolic engineering and fermentation of microorganisms for carotenoids production

H Eun, SY Lee - Current Opinion in Biotechnology, 2024 - Elsevier
Highlights•Systems metabolic engineering has enabled microbial-based carotenoids
production.•Metabolic flux optimization and enzyme assembly can enhance carotenoids …

Emerging nonmodel eukaryotes for biofuel production

L Hu, H Qiu, L Huang, F Zhang, VG Tran, J Yuan… - Current Opinion in …, 2023 - Elsevier
Highlights•Nonmodel eukaryotes feature superior characteristics conducive to biofuel
production.•Nonmodel eukaryotes have been engineered to produce bioethanol and …

The Genus Bryonia L. (Cucurbitaceae): A Systematic Review of Its Botany, Phytochemistry, Traditional Uses, and Biological Activities

B Benarba, K Belhouala - Sci, 2024 - mdpi.com
The Bryonia genus (Cucurbitaceae) is divided into 13 plants considered medicinal species
with a significant pharmacological value fortreating as well as preventing various ailments …