[HTML][HTML] Human papillomavirus vaccine against cervical cancer: Opportunity and challenge

R Wang, W Pan, L Jin, W Huang, Y Li, D Wu, C Gao… - Cancer letters, 2020 - Elsevier
Cervical cancer is one of the most common cancers threatening women's health, and the
persistent infection of high-risk human papillomavirus (HPV) is closely related to the …

Prophylactic and therapeutic HPV vaccines: current scenario and perspectives

Y Mo, J Ma, H Zhang, J Shen, J Chen… - Frontiers in cellular …, 2022 - frontiersin.org
Persistent human papillomavirus (HPV) infection is recognized as the main cause of cervical
cancer and other malignant cancers. Although early detection and treatment can be …

[HTML][HTML] Therapeutic vaccines for high-risk HPV-associated diseases

A Chabeda, RJR Yanez, R Lamprecht, AE Meyers… - Papillomavirus …, 2018 - Elsevier
Cancer is the second leading cause of death worldwide, and it is estimated that Human
papillomavirus (HPV) related cancers account for 5% of all human cancers. Current HPV …

The use of both therapeutic and prophylactic vaccines in the therapy of papillomavirus disease

AR Garbuglia, D Lapa, C Sias… - Frontiers in …, 2020 - frontiersin.org
Human papillomavirus (HPV) is the most common sexually transmitted virus. The high-risk
HPV types (ie, HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59) are considered to be the …

Perspectives for therapeutic HPV vaccine development

A Yang, E Farmer, TC Wu, CF Hung - Journal of biomedical science, 2016 - Springer
Background Human papillomavirus (HPV) infections and associated diseases remain a
serious burden worldwide. It is now clear that HPV serves as the etiological factor and …

Targeting persistent human papillomavirus infection

S Shanmugasundaram, J You - Viruses, 2017 - mdpi.com
While the majority of Human papillomavirus (HPV) infections are transient and cleared
within a couple of years following exposure, 10–20% of infections persist latently, leading to …

CD103+ tumor-infiltrating lymphocytes are tumor-reactive intraepithelial CD8+ T cells associated with prognostic benefit and therapy response in cervical cancer

FL Komdeur, TM Prins, S van de Wall, A Plat… - …, 2017 - Taylor & Francis
Human papilloma virus (HPV)-induced cervical cancer constitutively expresses viral E6/E7
oncoproteins and is an excellent target for T cell-based immunotherapy. However, not all …

Evolution of cancer vaccines—Challenges, achievements, and future directions

BQ Tay, Q Wright, R Ladwa, C Perry, G Leggatt… - Vaccines, 2021 - mdpi.com
The development of cancer vaccines has been intensively pursued over the past 50 years
with modest success. However, recent advancements in the fields of genetics, molecular …

Therapeutic HPV vaccines

G Hancock, K Hellner, L Dorrell - … practice & research Clinical obstetrics & …, 2018 - Elsevier
Highlights•Current prophylactic vaccines protect only against infection with high risk types
HPV16 and 18.•Several new platform technologies are being applied to the development of …

[HTML][HTML] Human papillomavirus-associated head and neck cancers. Where are we now? A systematic review

M Pinkiewicz, K Dorobisz, T Zatoński - Cancer Management and …, 2022 - ncbi.nlm.nih.gov
Background Human papillomavirus targets the skin and mucous membranes, producing
benign hyperplastic lesions and precancerous and cancerous lesions. An increasing …