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Connective tissue is known to provide structural and functional'glue'properties to other
tissues. It contains cellular and molecular components that are arranged in several dynamic …

Compositions and methods for treatment of aortic disease in a subject in need comprising
an effective amount of cobi namide. Aortic diseases include for example aortic aneu rysm …

Les fibres élastiques sont constituées d'élastine et de microfibrilles riches en fibrilline-1, dont
les mutations génétiques respectives conduisent à des pathologies cardiovasculaires …

Les grosses artères permettent au système vasculaire d'être plus qu'une simple voie de
circulation du sang dans l'organisme. Les fibres élastiques présentes dans la paroi de ces …

Das Marfan-Syndrom (MFS) ist eine relativ häufige autosomal dominant vererbte Störung
des Bindegewebes mit zahlreichen Symptomen im Skelettsystem, am Auge, und im …

The objective of the present study was to 1) analyze the ascending aortic proteome within a
mouse model of Marfan syndrome (MFS; Fbn1 C1041G/+) at early and late stages of …

Marfan syndrome (MFS), a connective tissue disorder triggered by mutations in Fibrillin-1,
causes life-threatening pathology including aortic aneurysm. Recently, controversy has …

The role of oxidative stress in different aortopathies is evaluated. Thirty-two tissue samples
from 18 men and 1 women were divided into: control (C) subjects, 11 patients with systemic …

Marfan syndrome (MFS) is associated with progressive aortic dilatation, endothelial
dysfunction, and oxidative stress that contribute to the early acute dissection of the vessel …