Dipeptidyl peptidase 3 (DPP3), a zinc‐dependent aminopeptidase, is a highly conserved
enzyme among higher animals. The enzyme cleaves dipeptides from the N‐terminus of tetra …

Sepsis represents one of the major medical challenges of the 21st century. Despite
substantial improvements in the knowledge on pathophysiological mechanisms, this has so …

Aims Acute heart failure is a high mortality disease and its pathophysiology is not completely
understood. Dipeptidyl peptidase 3 (DPP3) is a cytosolic enzyme involved in angiotensin II …

Abstract Aims Dipeptidyl peptidase 3 (DPP3) is a protease involved in the degradation of
cardiovascular mediators. Its administration has been shown to be associated with impaired …

Abstract Background Dipeptidyl peptidase 3 (DPP3) is a cytosolic enzyme involved in the
degradation of various cardiovascular and endorphin mediators. High levels of circulating …

Dipeptidyl peptidase 3 (DPP3) is a zinc-dependent hydrolase involved in degrading
oligopeptides with 4–12 amino acid residues. It has been associated with several …

Sepsis is a global economic and health burden. Dipeptidyl peptidase 3 (DPP3) is elevated
in the plasma of septic patients. The highest levels of circulating DPP3 (cDPP3) are found in …

Abstract Background Dipeptidyl peptidase-3 (DPP3) is a metallopeptidase which cleaves
bioactive peptides, notably angiotensin II, and is involved in inflammation regulation. DPP3 …

Purpose: Adrecizumab, a non-neutralizing antibody of adrenomedullin (ADM) was recently
investigated regarding its potential to restore endothelial barrier function in septic shock …

Introduction Dipeptidyl peptidase-3 (DPP3) is a protease involved in the degradation of
several cardiovascular mediators. Adrenomedullin (bio-ADM) is a peptide essential for …