Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 women: results from the European Prevention of …

RNM Saleh, M Hornberger, CW Ritchie… - Alzheimer's research & …, 2023 - Springer
Background The risk of dementia is higher in women than men. The metabolic
consequences of estrogen decline during menopause accelerate neuropathology in …

Changing demography and the challenge of dementia in India

V Ravindranath, JS Sundarakumar - Nature Reviews Neurology, 2021 - nature.com
In India, increasing lifespan and decreasing fertility rates have resulted in a growing number
of older persons. By 2050, people over 60 years of age are predicted to constitute 19.1% of …

A logical network-based drug-screening platform for Alzheimer's disease representing pathological features of human brain organoids

JC Park, SY Jang, D Lee, J Lee, U Kang… - Nature …, 2021 - nature.com
Developing effective drugs for Alzheimer's disease (AD), the most common cause of
dementia, has been difficult because of complicated pathogenesis. Here, we report an …

[HTML][HTML] Exposure to polystyrene microplastics impairs hippocampus-dependent learning and memory in mice

CW Lee, LF Hsu, IL Wu, YL Wang, WC Chen… - Journal of hazardous …, 2022 - Elsevier
Microplastics (MPs) pollution has become a serious environmental issue worldwide, but its
potential effects on health remain unknown. The administration of polystyrene MPs (PS …

Como elaborar uma revisão integrativa: sistematização do método científico

HL de Lima Dantas, CRB Costa, LMC Costa… - … -Revista Científica de …, 2022 - recien.com.br
Este estudo, a fim de apresentar sistematicamente os procedimentos científicos e
metodológicos elementares de uma Revisão Integrativa de Literatura, se estruturou …

Probiotics for Alzheimer's disease: a systematic review

R Naomi, H Embong, F Othman, HF Ghazi, N Maruthey… - Nutrients, 2021 - mdpi.com
Alzheimer's disease (AD) is the most common form of neurodegenerative disorders affecting
mostly the elderly. It is characterized by the presence of Aβ and neurofibrillary tangles (NFT) …

Hospital-treated infectious diseases and the risk of dementia: a large, multicohort, observational study with a replication cohort

PN Sipilä, N Heikkilä, JV Lindbohm… - The Lancet Infectious …, 2021 - thelancet.com
Background Infections have been hypothesised to increase the risk of dementia. Existing
studies have included a narrow range of infectious diseases, relied on short follow-up …

Charting a sustainable future: the impact of economic policy, environmental taxation, innovation, and natural resources on clean energy consumption

S Su, M Qamruzzaman, S Karim - Sustainability, 2023 - mdpi.com
Energy availability especially that derived from renewable sources has sustainable effects
on economic progress and environmental rectifications. However, using clean energy in the …

Long-term effects of cholinesterase inhibitors on cognitive decline and mortality

H Xu, S Garcia-Ptacek, L Jönsson, A Wimo… - Neurology, 2021 - AAN Enterprises
Objective To investigate whether cholinesterase inhibitors (ChEIs) are associated with
slower cognitive decline in Alzheimer dementia and decreased risk of severe dementia or …

Human neural cell type‐specific extracellular vesicle proteome defines disease‐related molecules associated with activated astrocytes in Alzheimer's disease brain

Y You, S Muraoka, MP Jedrychowski… - Journal of …, 2022 - Wiley Online Library
In neurodegenerative diseases, extracellular vesicles (EVs) transfer pathogenic molecules
and are consequently involved in disease progression. We have investigated the proteomic …