Hormone replacement therapy is associated with improved cognition and larger brain volumes in at-risk APOE4 women: results from the European Prevention of …
Background The risk of dementia is higher in women than men. The metabolic
consequences of estrogen decline during menopause accelerate neuropathology in …
consequences of estrogen decline during menopause accelerate neuropathology in …
Changing demography and the challenge of dementia in India
V Ravindranath, JS Sundarakumar - Nature Reviews Neurology, 2021 - nature.com
In India, increasing lifespan and decreasing fertility rates have resulted in a growing number
of older persons. By 2050, people over 60 years of age are predicted to constitute 19.1% of …
of older persons. By 2050, people over 60 years of age are predicted to constitute 19.1% of …
A logical network-based drug-screening platform for Alzheimer's disease representing pathological features of human brain organoids
JC Park, SY Jang, D Lee, J Lee, U Kang… - Nature …, 2021 - nature.com
Developing effective drugs for Alzheimer's disease (AD), the most common cause of
dementia, has been difficult because of complicated pathogenesis. Here, we report an …
dementia, has been difficult because of complicated pathogenesis. Here, we report an …
[HTML][HTML] Exposure to polystyrene microplastics impairs hippocampus-dependent learning and memory in mice
CW Lee, LF Hsu, IL Wu, YL Wang, WC Chen… - Journal of hazardous …, 2022 - Elsevier
Microplastics (MPs) pollution has become a serious environmental issue worldwide, but its
potential effects on health remain unknown. The administration of polystyrene MPs (PS …
potential effects on health remain unknown. The administration of polystyrene MPs (PS …
Como elaborar uma revisão integrativa: sistematização do método científico
Este estudo, a fim de apresentar sistematicamente os procedimentos científicos e
metodológicos elementares de uma Revisão Integrativa de Literatura, se estruturou …
metodológicos elementares de uma Revisão Integrativa de Literatura, se estruturou …
Probiotics for Alzheimer's disease: a systematic review
Alzheimer's disease (AD) is the most common form of neurodegenerative disorders affecting
mostly the elderly. It is characterized by the presence of Aβ and neurofibrillary tangles (NFT) …
mostly the elderly. It is characterized by the presence of Aβ and neurofibrillary tangles (NFT) …
Hospital-treated infectious diseases and the risk of dementia: a large, multicohort, observational study with a replication cohort
PN Sipilä, N Heikkilä, JV Lindbohm… - The Lancet Infectious …, 2021 - thelancet.com
Background Infections have been hypothesised to increase the risk of dementia. Existing
studies have included a narrow range of infectious diseases, relied on short follow-up …
studies have included a narrow range of infectious diseases, relied on short follow-up …
Charting a sustainable future: the impact of economic policy, environmental taxation, innovation, and natural resources on clean energy consumption
S Su, M Qamruzzaman, S Karim - Sustainability, 2023 - mdpi.com
Energy availability especially that derived from renewable sources has sustainable effects
on economic progress and environmental rectifications. However, using clean energy in the …
on economic progress and environmental rectifications. However, using clean energy in the …
Long-term effects of cholinesterase inhibitors on cognitive decline and mortality
Objective To investigate whether cholinesterase inhibitors (ChEIs) are associated with
slower cognitive decline in Alzheimer dementia and decreased risk of severe dementia or …
slower cognitive decline in Alzheimer dementia and decreased risk of severe dementia or …
Human neural cell type‐specific extracellular vesicle proteome defines disease‐related molecules associated with activated astrocytes in Alzheimer's disease brain
Y You, S Muraoka, MP Jedrychowski… - Journal of …, 2022 - Wiley Online Library
In neurodegenerative diseases, extracellular vesicles (EVs) transfer pathogenic molecules
and are consequently involved in disease progression. We have investigated the proteomic …
and are consequently involved in disease progression. We have investigated the proteomic …