LncRNAs in cancer: regulatory and therapeutic implications

A Nandwani, S Rathore, M Datta - Cancer letters, 2021 - Elsevier
Long noncoding RNAs (lncRNAs) comprise a class of RNAs that do not code for proteins but
are critical in regulating diverse cellular processes and maintaining cell function. In doing so …

[HTML][HTML] The emerging role of non-coding RNAs in the regulation of PI3K/AKT pathway in the carcinogenesis process

S Ghafouri-Fard, A Abak, FT Anamag, H Shoorei… - Biomedicine & …, 2021 - Elsevier
Abstract The PI3K/AKT pathway is an intracellular signaling pathway with an indispensable
impact on cell cycle control. This pathway is functionally related with cell proliferation, cell …

CNIT: a fast and accurate web tool for identifying protein-coding and long non-coding transcripts based on intrinsic sequence composition

JC Guo, SS Fang, Y Wu, JH Zhang, Y Chen… - Nucleic acids …, 2019 - academic.oup.com
As more and more high-throughput data has been produced by next-generation
sequencing, it is still a challenge to classify RNA transcripts into protein-coding or non …

The role of long non-coding RNAs in the tumor immune microenvironment

Y Guo, Y Xie, Y Luo - Frontiers in Immunology, 2022 - frontiersin.org
Tumorigenesis is a complicated process caused by successive genetic and epigenetic
alterations. The past decades demonstrated that the immune system affects tumorigenesis …

MYC-regulated lncRNA NEAT1 promotes B cell proliferation and lymphomagenesis via the miR-34b-5p-GLI1 pathway in diffuse large B-cell lymphoma

CS Qian, LJ Li, HW Huang, HF Yang, DP Wu - Cancer Cell International, 2020 - Springer
Background LncRNA NEAT1 has been identified as a tumour driver in many human
cancers. However, the underlying mechanism of lncRNA NEAT1 in diffuse large B-cell …

Diversity of rainbow trout blood B cells revealed by single cell RNA sequencing

P Perdiguero, E Morel, C Tafalla - Biology, 2021 - mdpi.com
Simple Summary Although evolutionarily jawed fish constitute the first group of animals in
which a complete adaptive immune system based on immunoglobulins (Igs) is present …

[HTML][HTML] Long non-coding RNAs and immune cells: Unveiling the role in viral infections

D Zhang, M Zhang, L Zhang, W Wang, S Hua… - Biomedicine & …, 2024 - Elsevier
Viral infections present significant challenges to human health, underscoring the importance
of understanding the immune response for effective therapeutic strategies. Immune cell …

Long non-coding RNA signatures in Lymphopoiesis and lymphoid malignancies

H Baghdadi, R Heidari, M Zavvar, N Ahmadi… - Non-coding RNA, 2023 - mdpi.com
Lymphoid cells play a critical role in the immune system, which includes three subgroups of
T, B, and NK cells. Recognition of the complexity of the human genetics transcriptome in …

Long non‑coding RNAs in multiple myeloma

C Yang, Y Liang, J Shu, S Wang… - International …, 2023 - spandidos-publications.com
Multiple myeloma (MM) is one of the three major malignancies of the hematological system
in middle‑aged and older individuals. The incidence of MM increases with age and due to its …

[PDF][PDF] STAT3-induced upregulation of lncRNA DUXAP8 functions as ceRNA for miR-577 to promote the migration and invasion in colorectal cancer through the …

C Du, HX Wang, P Chen… - European Review for …, 2019 - europeanreview.org
OBJECTIVE: Previous reports have shown that long non-coding RNAs (lncRNAs) are
involved in a series of biological processes and cancer in humans. Recently, lncRNA double …