Context: The effects of GH replacement therapy in patients who develop GH deficiency
(GHD) after cure of acromegaly have not been established in a placebo-controlled study …

Objective To define the appropriate diagnostic cut-off limits for the GH response to GHRH+
arginine (ARG) test and IGF-I levels, using receiver operating characteristics (ROC) curve …

Objective: The clinical features of adult GH deficiency (GHD) are nonspecific, and GH
stimulation testing is often required to confirm the diagnosis. However, diagnosing adult …

Objective To report a novel clinical and genetic presentation of a patient with 4H syndrome,
which is a recently described leukodystrophy syndrome characterized by ataxia …

GH secretion is controlled by hypothalamic as well as intrapituitary and peripheral signals,
all of which converge upon the somatotroph, resulting in integrated GH synthesis and …

Objective Recent investigations have provided evidence for a high prevalence of pituitary
dysfunction in patients with subarachnoid haemorrhage (SAH). However, apart from one …

Background and objective Previous studies on hypopituitarism and mortality have
concluded that insufficient pituitary function is associated with decreased survival. For …

After traumatic brain injury (TBI), patients present with psychological disorders that may be
explained by post-traumatic pituitary insufficiency (PI). The goal of this study was to …

Context: Both GH deficiency (GHD) and GH excess are associated with a decreased quality
of life. However, it is unknown whether patients with GHD after treatment for acromegaly …

We critically evaluated the diagnostic value of IGF-I and IGF-binding protein-3 (IGFBP-3) in
GH deficiency (GHD) in children and adults using receiver operating characteristic (ROC) …