TAK1 inhibition attenuates both inflammation and fibrosis in experimental pneumoconiosis
Pneumoconiosis, caused by inhalation of mineral dusts, is a major occupational disease
worldwide. Currently, there are no effective drugs owing to a lack of potential therapeutic …
worldwide. Currently, there are no effective drugs owing to a lack of potential therapeutic …
Immunity to the Dual Threat of Silica Exposure and Mycobacterium tuberculosis
P Konečný, R Ehrlich, M Gulumian… - Frontiers in …, 2019 - frontiersin.org
Exposure to silica and the consequent development of silicosis are well-known health
problems in countries with mining and other dust producing industries. Apart from its direct …
problems in countries with mining and other dust producing industries. Apart from its direct …
Small mine size is associated with lung function abnormality and pneumoconiosis among underground coal miners in Kentucky, Virginia and West Virginia
DJ Blackley, CN Halldin, ML Wang… - Occupational and …, 2014 - oem.bmj.com
Objectives To describe the prevalence of lung function abnormality and coal workers'
pneumoconiosis (CWP) by mine size among underground coal miners in Kentucky, Virginia …
pneumoconiosis (CWP) by mine size among underground coal miners in Kentucky, Virginia …
Inflammatory indices obtained from routine blood tests show an inflammatory state associated with disease progression in engineered stone silicosis patients
A García-Núñez, G Jiménez-Gómez… - Scientific reports, 2022 - nature.com
Patients with silicosis caused by occupational exposure to engineered stone (ES) present a
rapid progression from simple silicosis (SS) to progressive massive fibrosis (PMF). Patient …
rapid progression from simple silicosis (SS) to progressive massive fibrosis (PMF). Patient …
Global scenarios of metal mining, environmental repercussions, public policies, and sustainability: a review
LR Pokhrel, B Dubey - Critical Reviews in Environmental Science …, 2013 - Taylor & Francis
With rising valuation of mineral commodities, mining has been envisioned as a profitable
industry regardless of many challenges it entails. This comprehensive review provides the …
industry regardless of many challenges it entails. This comprehensive review provides the …
Club cell protein 16 as a biomarker for early detection of silicosis
N Naha, JCJ Muhamed, A Pagdhune… - Indian Journal of …, 2020 - journals.lww.com
Methods: This pilot study included 121 individuals from X-ray-confirmed/advanced silicosis,
moderate silica dust-exposed workers and healthy controls from western India. CC16 levels …
moderate silica dust-exposed workers and healthy controls from western India. CC16 levels …
[PDF][PDF] Polyhydroxylated C60 fullerene (fullerenol) attenuates neutrophilic lung inflammation in mice
M Roursgaard, S Poulsen, C Kepley… - Basic & clinical …, 2008 - core.ac.uk
Inflammation is crucial to eliminate pathogens and promote repair of injured tissue.
However, excessive or persistent inflammation can contribute to tissue injury and the …
However, excessive or persistent inflammation can contribute to tissue injury and the …
The role of mitochondrial dysfunction in macrophages on SiO2‐induced pulmonary fibrosis: A review
J Zhao, S Li, S Du, Z Zhang - Journal of Applied Toxicology, 2024 - Wiley Online Library
Several epidemiologic and toxicological studies have widely regarded that mitochondrial
dysfunction is a popular molecular event in the process of silicosis from different …
dysfunction is a popular molecular event in the process of silicosis from different …
Pulmonary dysfunctions, oxidative stress and DNA damage in brick kiln workers
R Kaushik, F Khaliq… - Human & …, 2012 - journals.sagepub.com
Brick kilns in the suburban areas in developing countries pose a big threat to the
environment and hence the health of their workers and people residing around them. The …
environment and hence the health of their workers and people residing around them. The …
Physicochemical determinants in the cellular responses to nanostructured amorphous silicas
E Gazzano, M Ghiazza, M Polimeni, V Bolis… - Toxicological …, 2012 - academic.oup.com
Amorphous silicas, opposite to crystalline polymorphs, have been regarded so far as
nonpathogenic, but few studies have addressed the toxicity of the wide array of amorphous …
nonpathogenic, but few studies have addressed the toxicity of the wide array of amorphous …