Cytochrome P450 enzymes: central players in cardiovascular health and disease
RH Elbekai, AOS El-Kadi - Pharmacology & therapeutics, 2006 - Elsevier
Cardiovascular disease (CVD) is a human health crisis that remains the leading cause of
death worldwide. The cytochrome P450 (CYP) class of enzymes are key metabolizers of …
death worldwide. The cytochrome P450 (CYP) class of enzymes are key metabolizers of …
Association of the C− 344T aldosterone synthase gene variant with essential hypertension: a meta-analysis
S Sookoian, TF Gianotti, CD González… - Journal of …, 2007 - journals.lww.com
Background The CYP11B2 gene (CYP11B2) encoding aldosterone synthase has been
associated with essential hypertension and some, but not all, studies have reported that the …
associated with essential hypertension and some, but not all, studies have reported that the …
Modulation of cardiac and hepatic cytochrome P450 enzymes during heart failure
AOS El-Kadi, BNM Zordoky - Current drug metabolism, 2008 - ingentaconnect.com
Heart failure is a very serious cardiovascular disease that affects more than five million
people in North America. The role of cytochrome P450 (CYP) in cardiovascular health and …
people in North America. The role of cytochrome P450 (CYP) in cardiovascular health and …
C-344T polymorphism of the aldosterone synthase gene and blood pressure in the elderly: a population-based study
E Casiglia, V Tikhonoff, A Mazza… - Journal of …, 2005 - journals.lww.com
Objectives Whether the C-344T polymorphism of the aldosterone synthase gene is important
for blood pressure control remains controversial. It has been proposed that an association …
for blood pressure control remains controversial. It has been proposed that an association …
Association of HSD3B1 and HSD3B2 gene polymorphisms with essential hypertension, aldosterone level, and left ventricular structure
M Shimodaira, T Nakayama, N Sato… - European journal of …, 2010 - academic.oup.com
Abstract Background HSD3B1 and HSD3B2 are crucial enzymes for the synthesis of
hormonal steroids, including aldosterone. Therefore, HSD3B gene variations could possibly …
hormonal steroids, including aldosterone. Therefore, HSD3B gene variations could possibly …
[PDF][PDF] Association of the-344T/C aldosterone synthase gene variant with essential hypertension.
Z Hlubocká, M Jachymova, S Heller… - Physiological …, 2009 - academia.edu
The aldosterone synthase gene (CYP11B2) is an important candidate gene region in
essential hypertension. We therefore studied the association of-344T/C polymorphism of the …
essential hypertension. We therefore studied the association of-344T/C polymorphism of the …
Role of the C-344T aldosterone synthase gene variant in left ventricular mass and left ventricular structure-related phenotypes
S Sookoian, TF Gianotti, CJ Pirola - Heart, 2008 - heart.bmj.com
Aim: We performed a systematic review of the literature by means of a meta-analysis to
evaluate the influence of the aldosterone synthase gene (CYP11B2) C-344T polymorphism …
evaluate the influence of the aldosterone synthase gene (CYP11B2) C-344T polymorphism …
Association of echocardiographic left ventricular structure and− 344C/T aldosterone synthase gene variant: A meta-analysis
L Wang, J Zhou, B Zhang, H Wang… - Journal of the Renin …, 2015 - journals.sagepub.com
Background: Aldosterone synthase (CYP11B2) is one of the most studied candidate genes
related to essential hypertension (EH) and left ventricular hypertrophy (LVH). Some studies …
related to essential hypertension (EH) and left ventricular hypertrophy (LVH). Some studies …
Faktor risiko non genetik dan polimorfisme promoter regiongen CYP11B2Varian T (-344) C aldosterone synthasepada pasien hipertensi esensial di wilayah pantai …
S Sundari, D Wahono, MA Widodo - Jurnal Kedokteran Brawijaya, 2013 - jkb.ub.ac.id
Hipertensi  esensial  disebabkan  oleh  multifaktorial  dan  merupakan  penyakit Â
yang  kompleks  karena  melibatkan  faktor genetik  dan  lingkungan  atau  …
yang  kompleks  karena  melibatkan  faktor genetik  dan  lingkungan  atau  …
Association of the− 344T/C polymorphism in aldosterone synthase gene promoter with left ventricular structure in Chinese Han: A meta-analysis
C Yin, W Gu, Y Gao, Z Li, X Chen, Z Li… - Clinical and …, 2017 - Taylor & Francis
No consensus view has been published on the relationship between the aldosterone
synthase gene (CYP11B2)− 344C/T polymorphism and left ventricular hypertrophy (LVH) in …
synthase gene (CYP11B2)− 344C/T polymorphism and left ventricular hypertrophy (LVH) in …