Widespread Doublecortin Expression in the Cerebral Cortex of the Octodon degus

T Van Groen, I Kadish, N Popović… - Frontiers in …, 2021 - frontiersin.org
It has been demonstrated that in adulthood rodents show newly born neurons in the
subgranular layer (SGL) of the dentate gyrus (DG), and in the subventricular zone (SVZ) …

Биологические основы амилоидоза при болезни Альцгеймера

ТВ Андреева, УД Лукив, ЕИ Рогаев - Биохимия, 2017 - elibrary.ru
Некоторые растворимые в норме клеточные белки при определенных условиях
образуют т. н. амилоиды нерастворимые белковые фибриллы со специфической …

Spatial maps and oscillations in the healthy hippocampus of Octodon degus, a natural model of sporadic Alzheimer's disease

M Mugnaini, D Polania, Y Diaz, M Ezquer, F Ezquer… - Scientific Reports, 2022 - nature.com
The Octodon degus is a South American rodent that is receiving increased attention as a
potential model of aging and sporadic late-onset Alzheimer's disease (AD). Impairments in …

A New Tool to Study Parkinsonism in the Context of Aging: MPTP Intoxication in a Natural Model of Multimorbidity

L Cuenca, E Pizzichini, VC Gonçalves, M Guillén-Díaz… - 2024 - digitum.um.es
The diurnal rodent Octodon degus (O. degus) is considered an attractive natural model for
Alzheimer's disease and other human age-related features. However, it has not been …

Immunohistochemical identification of the extravillous trophoblast during the placentation of the degu (Octodon degus)

C Bosco, C Buffet - Journal of Experimental Zoology Part B …, 2008 - Wiley Online Library
Recent data indicate that placentation in Octodon degus is similar to that in humans, making
it a potential animal model for studies in human placental pathologies related to alterations …

Advances in retinal imaging: retinal amyloid imaging

M Koronyo-Hamaoui, J Doustar, M Oviatt… - … The Eye as a Window to …, 2020 - Springer
Growing evidence indicates that the brain is not the only CNS tissue affected by Alzheimer's
disease (AD) pathology—the retina is also afflicted with the pathological hallmarks Aβ and …

Preputial damage and lateral penile displacement during castration in a degu

MY Powers, BG Campbell… - Journal of the American …, 2008 - Am Vet Med Assoc
Abstract Case Description—A 2-month-old male degu was treated for preputial damage and
lateral penile displacement that occurred during attempted castration. Clinical Findings …

Differential Role of Sex and Age in the Synaptic Transmission of Degus (Octodon degus)

CA Oliva, DS Rivera, TA Mariqueo… - Frontiers in Integrative …, 2022 - frontiersin.org
Octodon degus are a diurnal long-lived social animal widely used to perform longitudinal
studies and complex cognitive tasks to test for physiological conditions with similitude in …

Degus

M Kubiak - Handbook of Exotic Pet Medicine, 2020 - Wiley Online Library
Degus (Octodon degus) are a medium sized rodent classified as part of the Hystricomorph
family, along with guinea pigs, chinchillas, and porcupines. They are herbivorous and …

Effects of Vitamin D Receptor (VDR), Age and Cholesterol-Status on Aβ Peptide Accumulation in the Brain

HB Peng - 2022 - search.proquest.com
Alzheimer's disease (AD) is associated with accumulation of toxic amyloid-beta peptides, 40
and 42 amino acid lengths (Aβ 40 and Aβ 42) in brain. Calcitriol, natural ligand of the vitamin …