[PDF][PDF] Identification of Triple Negative Breast Cancer Genes Using Rough Set Based Feature Selection Algorithm & Ensemble Classifier

S Patil, KR Balmuri, J Frnda… - … -centric computing and …, 2022 - hcisj.com
In recent decades, microarray datasets have played an important role in triple negative
breast cancer (TNBC) detection. Microarray data classification is a challenging process due …

[HTML][HTML] Overview of methods for characterization and visualization of a protein–protein interaction network in a multi-omics integration context

V Robin, A Bodein, MP Scott-Boyer… - Frontiers in Molecular …, 2022 - frontiersin.org
At the heart of the cellular machinery through the regulation of cellular functions, protein–
protein interactions (PPIs) have a significant role. PPIs can be analyzed with network …

Prediction of drug side effects with a refined negative sample selection strategy

H Liang, L Chen, X Zhao… - … and Mathematical Methods …, 2020 - Wiley Online Library
Drugs are an important way to treat various diseases. However, they inevitably produce side
effects, bringing great risks to human bodies and pharmaceutical companies. How to predict …

Identification of COVID‐19 infection‐related human genes based on a random walk model in a virus–human protein interaction network

YH Zhang, T Zeng, L Chen, SJ Ding… - BioMed research …, 2020 - Wiley Online Library
Coronaviruses are specific crown‐shaped viruses that were first identified in the 1960s, and
three typical examples of the most recent coronavirus disease outbreaks include severe …

DDK-Linker: a network-based strategy identifies disease signals by linking high-throughput omics datasets to disease knowledge

X Kong, L Diao, P Jiang, S Nie, S Guo… - Briefings in …, 2024 - academic.oup.com
The high-throughput genomic and proteomic scanning approaches allow investigators to
measure the quantification of genome-wide genes (or gene products) for certain disease …

[HTML][HTML] RWR-algorithm-based dissection of microRNA-506-3p and microRNA-140-5p as radiosensitive biomarkers in colorectal cancer

F Liao, X Chen, P Peng, W Dong - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Radiotherapy resistance is one of the main causes for treatment failure in colorectal cancer
(CRC), and it is associated with the deregulation of certain microRNAs. In this study, we …

[HTML][HTML] PWN: enhanced random walk on a warped network for disease target prioritization

S Han, J Hong, SJ Yun, HJ Koo, TY Kim - BMC bioinformatics, 2023 - Springer
Background Extracting meaningful information from unbiased high-throughput data has
been a challenge in diverse areas. Specifically, in the early stages of drug discovery, a …

[HTML][HTML] Capilliposide B blocks VEGF-induced angiogenesis in vitro in primary human retinal microvascular endothelial cells

H Han, Y Yang, Z Wu, B Liu, L Dong, H Deng… - Biomedicine & …, 2021 - Elsevier
Abnormal angiogenesis is associated with intraocular diseases such as proliferative diabetic
retinopathy and neovascular age-related macular degeneration, and current therapies for …

A path-based method for identification of protein phenotypic annotations

J Gao, B Hu, L Chen - Current Bioinformatics, 2021 - ingentaconnect.com
Background: Identification of protein phenotypic annotations is an essential and challenging
problem in modern genetics. Such problem is related to some serious diseases, including …

Prediction of drug combinations with a network embedding method

T Wang, L Chen, X Zhao - Combinatorial Chemistry & High …, 2018 - ingentaconnect.com
Aim and Objective: There are several diseases having a complicated mechanism. For such
complicated diseases, a single drug cannot treat them very well because these diseases …