[PDF][PDF] Identification of Triple Negative Breast Cancer Genes Using Rough Set Based Feature Selection Algorithm & Ensemble Classifier
In recent decades, microarray datasets have played an important role in triple negative
breast cancer (TNBC) detection. Microarray data classification is a challenging process due …
breast cancer (TNBC) detection. Microarray data classification is a challenging process due …
[HTML][HTML] Overview of methods for characterization and visualization of a protein–protein interaction network in a multi-omics integration context
V Robin, A Bodein, MP Scott-Boyer… - Frontiers in Molecular …, 2022 - frontiersin.org
At the heart of the cellular machinery through the regulation of cellular functions, protein–
protein interactions (PPIs) have a significant role. PPIs can be analyzed with network …
protein interactions (PPIs) have a significant role. PPIs can be analyzed with network …
Prediction of drug side effects with a refined negative sample selection strategy
H Liang, L Chen, X Zhao… - … and Mathematical Methods …, 2020 - Wiley Online Library
Drugs are an important way to treat various diseases. However, they inevitably produce side
effects, bringing great risks to human bodies and pharmaceutical companies. How to predict …
effects, bringing great risks to human bodies and pharmaceutical companies. How to predict …
Identification of COVID‐19 infection‐related human genes based on a random walk model in a virus–human protein interaction network
Coronaviruses are specific crown‐shaped viruses that were first identified in the 1960s, and
three typical examples of the most recent coronavirus disease outbreaks include severe …
three typical examples of the most recent coronavirus disease outbreaks include severe …
DDK-Linker: a network-based strategy identifies disease signals by linking high-throughput omics datasets to disease knowledge
X Kong, L Diao, P Jiang, S Nie, S Guo… - Briefings in …, 2024 - academic.oup.com
The high-throughput genomic and proteomic scanning approaches allow investigators to
measure the quantification of genome-wide genes (or gene products) for certain disease …
measure the quantification of genome-wide genes (or gene products) for certain disease …
[HTML][HTML] RWR-algorithm-based dissection of microRNA-506-3p and microRNA-140-5p as radiosensitive biomarkers in colorectal cancer
F Liao, X Chen, P Peng, W Dong - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Radiotherapy resistance is one of the main causes for treatment failure in colorectal cancer
(CRC), and it is associated with the deregulation of certain microRNAs. In this study, we …
(CRC), and it is associated with the deregulation of certain microRNAs. In this study, we …
[HTML][HTML] PWN: enhanced random walk on a warped network for disease target prioritization
Background Extracting meaningful information from unbiased high-throughput data has
been a challenge in diverse areas. Specifically, in the early stages of drug discovery, a …
been a challenge in diverse areas. Specifically, in the early stages of drug discovery, a …
[HTML][HTML] Capilliposide B blocks VEGF-induced angiogenesis in vitro in primary human retinal microvascular endothelial cells
H Han, Y Yang, Z Wu, B Liu, L Dong, H Deng… - Biomedicine & …, 2021 - Elsevier
Abnormal angiogenesis is associated with intraocular diseases such as proliferative diabetic
retinopathy and neovascular age-related macular degeneration, and current therapies for …
retinopathy and neovascular age-related macular degeneration, and current therapies for …
A path-based method for identification of protein phenotypic annotations
J Gao, B Hu, L Chen - Current Bioinformatics, 2021 - ingentaconnect.com
Background: Identification of protein phenotypic annotations is an essential and challenging
problem in modern genetics. Such problem is related to some serious diseases, including …
problem in modern genetics. Such problem is related to some serious diseases, including …
Prediction of drug combinations with a network embedding method
T Wang, L Chen, X Zhao - Combinatorial Chemistry & High …, 2018 - ingentaconnect.com
Aim and Objective: There are several diseases having a complicated mechanism. For such
complicated diseases, a single drug cannot treat them very well because these diseases …
complicated diseases, a single drug cannot treat them very well because these diseases …