[HTML][HTML] miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review
Among deregulated microRNAs (miRs) in human malignancies, miR-221 has been widely
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …
Cancer-derived exosomal miR-221-3p promotes angiogenesis by targeting THBS2 in cervical squamous cell carcinoma
XG Wu, CF Zhou, YM Zhang, RM Yan, WF Wei… - Angiogenesis, 2019 - Springer
Aims Recently, cancer-derived exosomes were shown to have pro-metastasis function in
cancer, but the mechanism remains unclear. Angiogenesis is essential for tumor …
cancer, but the mechanism remains unclear. Angiogenesis is essential for tumor …
[HTML][HTML] Circulating RNA in kidney cancer: What we know and what we still suppose
A Cinque, R Vago, F Trevisani - Genes, 2021 - mdpi.com
Renal cancer represents the 7th most common tumor worldwide, affecting 400,000 people
annually. This malignancy, which is the third most frequent cancer among urological …
annually. This malignancy, which is the third most frequent cancer among urological …
[HTML][HTML] Plasma exosomal miRNAs-based prognosis in metastatic kidney cancer
Plasma exosomal miRNAs were evaluated for prognosis in an initial set of 44 metastatic
renal cell cancer (mRCC) patients by RNA sequencing. Among∼ 3.49 million mappable …
renal cell cancer (mRCC) patients by RNA sequencing. Among∼ 3.49 million mappable …
[HTML][HTML] Plasmatic miR-210, miR-221 and miR-1233 profile: potential liquid biopsies candidates for renal cell carcinoma
F Dias, AL Teixeira, M Ferreira, B Adem, N Bastos… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Renal cell carcinoma (RCC) represents a challenge for clinicians since the nonexistence of
screening and monitoring tests contributes to the fact that one-third of patients are …
screening and monitoring tests contributes to the fact that one-third of patients are …
[HTML][HTML] MicroRNAs targeting HIF-2α, VEGFR1 and/or VEGFR2 as potential predictive biomarkers for VEGFR tyrosine kinase and HIF-2α inhibitors in metastatic clear …
Simple Summary Metastatic clear-cell renal cell carcinoma is characterized by heightened
angiogenesis through increased expression of HIF-2α and VEGFR2. VEGFR tyrosine kinase …
angiogenesis through increased expression of HIF-2α and VEGFR2. VEGFR tyrosine kinase …
EGF receptor inhibition by erlotinib increases aquaporin 2–mediated renal water reabsorption
Nephrogenic diabetes insipidus (NDI) is caused by impairment of vasopressin (VP) receptor
type 2 signaling. Because potential therapies for NDI that target the canonical …
type 2 signaling. Because potential therapies for NDI that target the canonical …
[HTML][HTML] Deep sequencing reveals microRNAs predictive of antiangiogenic drug response
J García-Donas, B Beuselinck, L Inglada-Pérez… - JCI insight, 2016 - ncbi.nlm.nih.gov
The majority of metastatic renal cell carcinoma (RCC) patients are treated with tyrosine
kinase inhibitors (TKI) in first-line treatment; however, a fraction are refractory to these …
kinase inhibitors (TKI) in first-line treatment; however, a fraction are refractory to these …
[HTML][HTML] Cancer cells' metabolism dynamics in renal cell carcinoma patients' outcome: Influence of GLUT-1-Related hsa-miR-144 and hsa-miR-186
M Morais, F Dias, I Nogueira, A Leão, N Gonçalves… - Cancers, 2021 - mdpi.com
Simple Summary Renal cell carcinoma (RCC) is a metabolic associated cancer and the
most common and lethal neoplasia in the adult kidney. This study aimed to understand the …
most common and lethal neoplasia in the adult kidney. This study aimed to understand the …
[HTML][HTML] Screening and identification of key biomarkers of papillary renal cell carcinoma by bioinformatic analysis
Y Xu, D Kong, Z Li, L Qian, J Li, C Zou - Plos one, 2021 - journals.plos.org
Background Papillary renal cell carcinoma (PRCC) is the most common type of renal cell
carcinoma after clear cell renal cell carcinoma (ccRCC). Its pathological classification is …
carcinoma after clear cell renal cell carcinoma (ccRCC). Its pathological classification is …