Carnitine is a conditionally essential nutrient that plays a vital role in energy production and
fatty acid metabolism. Vegetarians possess a greater bioavailability than meat eaters …

In recent years increasing evidence has emerged suggesting that oxidative stress is
involved in the pathophysiology of a number of inherited metabolic disorders. However the …

A random retrospective chart review was conducted to document serum carnitine levels on
100 children with autism. Concurrently drawn serum pyruvate, lactate, ammonia, and …

Carnitine is essential for β-oxidation of fatty acids, and a defect of cell membrane transport of
carnitine leads to fatal systemic carnitine deficiency. We have already shown that a defect of …

l-Carnitine (LC) is a naturally occurring quaternary ammonium compound endogenous in all
mammalian species and is a vital cofactor for the mitochondrial oxidation of fatty acids. Fatty …

One of the characteristic complaints of patients with chronic fatigue syndrome (CFS) is the
skeletal muscle-related symptom. However, the abnormalities in the skeletal muscle that …

The iron and 2-oxoacid-dependent dioxygenases are an important class of enzymes that
mediate a variety of oxidative reactions. Several general reviews on these enzymes have …

Carnitine is an important nutrient that is present in the diet (particularly in meat and dairy
products) and is synthesized from dietary amino acids. It functions to assist long-chain fatty …

Nodding syndrome (NS) is a debilitating yet often neglected neurological disease affecting
thousands of children in several sub-Saharan African countries. The cause of NS remains …

▪ Abstract Carnitine functions as a substrate for a family of enzymes, carnitine
acyltransferases, involved in acyl-coenzyme A metabolism and as a carrier for long-chain …