Liquid biopsy, ctDNA diagnosis through NGS
C Lin, X Liu, B Zheng, R Ke, CM Tzeng - Life, 2021 - mdpi.com
Liquid biopsy with circulating tumor DNA (ctDNA) profiling by next-generation sequencing
holds great promise to revolutionize clinical oncology. It relies on the basis that ctDNA …
holds great promise to revolutionize clinical oncology. It relies on the basis that ctDNA …
Early detection of ovarian cancer
The rationale for early detection of ovarian cancer is compelling. Ovarian cancer confined to
the ovaries (stage I) can be cured in up to 90% of patients, and disease confined to the …
the ovaries (stage I) can be cured in up to 90% of patients, and disease confined to the …
Role of saliva and salivary diagnostics in the advancement of oral health
C Dawes, DTW Wong - Journal of dental research, 2019 - journals.sagepub.com
The objective of this article was to provide an account of some of the developments related
to saliva over the first 100 years of the Journal of Dental Research and to outline some of the …
to saliva over the first 100 years of the Journal of Dental Research and to outline some of the …
Genomic alterations in liquid biopsies from patients with bladder cancer
K Birkenkamp-Demtröder, I Nordentoft, E Christensen… - European urology, 2016 - Elsevier
Background At least half of the patients diagnosed with non–muscle-invasive bladder
cancer (NMIBC) experience recurrence and approximately 15% will develop progression to …
cancer (NMIBC) experience recurrence and approximately 15% will develop progression to …
New perspectives on the importance of cell-free DNA biology
AJ Bronkhorst, V Ungerer, A Oberhofer, S Gabriel… - Diagnostics, 2022 - mdpi.com
Body fluids are constantly replenished with a population of genetically diverse cell-free DNA
(cfDNA) fragments, representing a vast reservoir of information reflecting real-time changes …
(cfDNA) fragments, representing a vast reservoir of information reflecting real-time changes …
Novel approaches to ovarian cancer screening
DR Nebgen, KH Lu, RC Bast - Current oncology reports, 2019 - Springer
Abstract Purpose of Review Both conventional and novel approaches to early detection of
ovarian cancer are reviewed in the context of new developments in our understanding of …
ovarian cancer are reviewed in the context of new developments in our understanding of …
[HTML][HTML] Detection of ubiquitous and heterogeneous mutations in cell-free DNA from patients with early-stage non-small-cell lung cancer
M Jamal-Hanjani, GA Wilson, S Horswell, R Mitter… - Annals of …, 2016 - Elsevier
Background The aim of this pilot study was to assess whether both ubiquitous and
heterogeneous somatic mutations could be detected in cell-free DNA (cfDNA) from patients …
heterogeneous somatic mutations could be detected in cell-free DNA (cfDNA) from patients …
[HTML][HTML] “Liquid biopsy”—ctDNA detection with great potential and challenges
M Ma, H Zhu, C Zhang, X Sun, X Gao… - Annals of translational …, 2015 - ncbi.nlm.nih.gov
Circulating tumor DNA (ctDNA) is now being extensively studied as it is a noninvasive “real-
time” biomarker that can provide diagnostic and prognostic information before, during …
time” biomarker that can provide diagnostic and prognostic information before, during …
Tumor markers and their diagnostic significance in ovarian cancer
Ovarian cancer (OC) is characterized by silent progression and late-stage diagnosis. It is
critical to detect and accurately diagnose the disease early to improve survival rates. Tumor …
critical to detect and accurately diagnose the disease early to improve survival rates. Tumor …
[HTML][HTML] Non-blood circulating tumor DNA detection in cancer
Tumor DNA contains specific somatic alterations that are crucial for the diagnosis and
treatment of cancer. Due to the spatial and temporal intra-tumor heterogeneity, multi …
treatment of cancer. Due to the spatial and temporal intra-tumor heterogeneity, multi …