The pannexin family of mammalian proteins, composed of Panx1, Panx2, and Panx3, has
been postulated to be a new class of single-membrane channels with functional similarities …

In less than a decade, a small family of channel-forming glycoproteins, named pannexins,
have captured the interest of many biologists, in large part due to their association with …

Abstract Pannexin 2 (Panx2) is a large-pore ATP-permeable channel with critical roles in
various physiological processes, such as the inflammatory response, energy production and …

Intercellular communication (IC) is mediated by gap junctions (GJs) and hemichannels,
which consist of proteins. This has been particularly well documented for the connexin (Cx) …

Pannexin 3 (Panx3) is a new member of the gap junction pannexin family, but its expression
profiles and physiological function are not yet clear. We demonstrate in this study that Panx3 …

The pannexins (Panxs) are a family of chordate proteins homologous to the invertebrate gap
junction forming proteins named innexins. Three distinct Panx paralogs (Panx1, Panx2, and …

SRJ, BEI, and MK conceived this study, conceptualized, and provided financial backing. SRJ
and YY designed and executed the majority of the experiments. LJD, AKB, EM, and JM …

Pannexins (Panx) are a class of integral membrane proteins that have been proposed to
exhibit characteristics similar to those of connexin family members. In this study, we utilized …

Posttranslational modification is a common cellular process that is used by cells to ensure a
particular protein function. This can happen in a variety of ways, eg, from the addition of …

Pannexins are a family of integral membrane proteins with distinct post-translational
modifications, sub-cellular localization and tissue distribution. Panx1 is the most studied and …