Update on the mechanisms of liver regeneration

ME Preziosi, SP Monga - Seminars in liver disease, 2017 - thieme-connect.com
Liver possesses many critical functions such as synthesis, detoxification, and metabolism. It
continually receives nutrient-rich blood from gut, which incidentally is also toxin-rich. That …

Liver fibrosis in biliary atresia

WJ Shen, G Chen, M Wang, S Zheng - World Journal of Pediatrics, 2019 - Springer
Background Biliary atresia (BA) is the most common cause of obstructive jaundice in infants.
Although the Kasai procedure has greatly improved the prognosis, most patients still need …

miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1

M Mraz, L Chen, LZ Rassenti, EM Ghia… - Blood, The Journal …, 2014 - ashpublications.org
We examined the microRNAs (miRNAs) expressed in chronic lymphocytic leukemia (CLL)
and identified miR-150 as the most abundant, but with leukemia cell expression levels that …

A three–microRNA signature as a potential biomarker for the early detection of oral cancer

YA Chang, SL Weng, SF Yang, CH Chou… - International journal of …, 2018 - mdpi.com
Oral squamous cell carcinoma (OSCC) is often diagnosed at a late stage and may be
malignantly transformed from oral leukoplakia (OL). This study aimed to identify potential …

Comprehensive CircRNA expression profile and selection of key CircRNAs during priming phase of rat liver regeneration

L Li, J Guo, Y Chen, C Chang, C Xu - BMC genomics, 2017 - Springer
Background Rat liver regeneration (LR) proceeds along a process of highly organized and
ordered tissue growth in response to the loss or injury of liver tissue, during which many …

Endothelial microRNA-150 is an intrinsic suppressor of pathologic ocular neovascularization

CH Liu, Y Sun, J Li, Y Gong, KT Tian… - Proceedings of the …, 2015 - National Acad Sciences
Pathologic ocular neovascularization commonly causes blindness. It is critical to identify the
factors altered in pathologically proliferating versus normally quiescent vessels to develop …

MicroRNA‐150 regulates blood‐brain barrier permeability via Tie‐2 after permanent middle cerebral artery occlusion in rats

Z Fang, QW He, Q Li, XL Chen, S Baral… - The FASEB …, 2016 - Wiley Online Library
The mechanism of blood‐brain barrier (BBB) disruption, involved in poststroke edema and
hemorrhagic transformation, is important but elusive. We investigated microRNA‐150 (miR …

VEGF-a stimulus for neuronal development and regeneration in the CNS and PNS

V Theis, C Theiss - Current Protein and Peptide Science, 2018 - ingentaconnect.com
The vascular endothelial growth factor (VEGF) is a homodimeric disulfide bound
glycoprotein that promotes endothelial growth, accompanied by higher vascular …

Regulation of microRNAs and their role in liver development, regeneration and disease

ML Finch, JU Marquardt, GC Yeoh, BA Callus - The international journal of …, 2014 - Elsevier
Since their discovery more than a decade ago microRNAs have been demonstrated to have
profound effects on almost every aspect of biology. Numerous studies in recent years have …

Physical nanoscale conduit-mediated communication between tumour cells and the endothelium modulates endothelial phenotype

Y Connor, S Tekleab, S Nandakumar, C Walls… - Nature …, 2015 - nature.com
Metastasis is a major cause of mortality and remains a hurdle in the search for a cure for
cancer. Not much is known about metastatic cancer cells and endothelial cross-talk, which …