The arachidonic acid (AA) pathway plays a key role in cardiovascular biology,
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …

Exercise is typically one of the first management strategies advised for patients newly
diagnosed with type 2 diabetes. Together with diet and behavior modification, exercise is an …

The mechanistic target of rapamycin (mTOR) signaling pathway senses and integrates a
variety of environmental cues to regulate organismal growth and homeostasis. The pathway …

As obesity reaches epidemic proportions, nonalcoholic fatty liver disease (NAFLD) is
becoming a frequent cause of patient referral to gastroenterologists. There is a close link …

Diabetes mellitus and periodontal disease are chronic diseases affecting a large number of
populations worldwide. Changed bone metabolism is one of the important long-term …

Iron homeostasis is affected by obesity and obesity-related insulin resistance in a many-
facetted fashion. On one hand, iron deficiency and anemia are frequent findings in subjects …

Pre-diabetes represents an elevation of plasma glucose above the normal range but below
that of clinical diabetes. Pre-diabetes can be identified as either impaired fasting glucose …

Context Chronic obesity is associated with several complications, including cognitive
impairment and dementia. However, we have only piecemeal knowledge of the mechanisms …

The role of adipose tissue insulin resistance in the pathogenesis of nonalcoholic fatty liver
disease (NAFLD) remains unclear. To evaluate this, we measured in 207 patients with …

The lack of therapy and the failure of existing therapy has been a challenge for clinicians in
treating various cancers. Doxorubicin, 5-fluorouracil, cisplatin, and paclitaxel are the first-line …