Biology of obesity: lessons from animal models of obesity
K Kanasaki, D Koya - BioMed Research International, 2011 - Wiley Online Library
Obesity is an epidemic problem in the world and is associated with several health problems,
including diabetes, cardiovascular disease, respiratory failure, muscle weakness, and …
including diabetes, cardiovascular disease, respiratory failure, muscle weakness, and …
[PDF][PDF] Animal models of obesity
Background Obesity stems from a prolonged imbalance between the levels of energy intake
and expenditure, with the resultant surplus being stored as body lipids. Our understanding of …
and expenditure, with the resultant surplus being stored as body lipids. Our understanding of …
The contribution of animal models to the study of obesity
Obesity results from prolonged imbalance of energy intake and energy expenditure. Animal
models have provided a fundamental contribution to the historical development of …
models have provided a fundamental contribution to the historical development of …
Balancing ovulation and anovulation: integration of the reproductive and energy balance axes by neuropeptides
JJ Evans, GM Anderson - Human reproduction update, 2012 - academic.oup.com
BACKGROUND Because of the substantial energy demands of reproduction, the brain must
temper the fertility of individuals to match nutritional availability. Under-nutrition is associated …
temper the fertility of individuals to match nutritional availability. Under-nutrition is associated …
Chronic increase of circulating galanin levels induces obesity and marked alterations in lipid metabolism similar to metabolic syndrome
NJ Poritsanos, TM Mizuno, ME Lautatzis… - International Journal of …, 2009 - nature.com
Objective: Galanin (GAL) has a role in the regulation of food intake by way of acting on the
central nervous system in rodents. High serum GAL levels have been observed in obese …
central nervous system in rodents. High serum GAL levels have been observed in obese …
Feeding behaviour in galanin knockout mice supports a role of galanin in fat intake and preference
It has been widely suggested that saturated fat consumption has fuelled the current obesity
epidemic. Macronutrient choices appear to be important not only as potential factors …
epidemic. Macronutrient choices appear to be important not only as potential factors …
Dietary fat stimulates endogenous enkephalin and dynorphin in the paraventricular nucleus: role of circulating triglycerides
GQ Chang, O Karatayev, R Ahsan… - American Journal …, 2007 - journals.physiology.org
The opioid peptides enkephalin (ENK) and dynorphin (DYN), when injected into the
hypothalamus, are known to stimulate feeding behavior and preferentially increase the …
hypothalamus, are known to stimulate feeding behavior and preferentially increase the …
Galanin type 1 receptor knockout mice show altered responses to high-fat diet and glucose challenge
EP Zorrilla, M Brennan, V Sabino, X Lu, T Bartfai - Physiology & behavior, 2007 - Elsevier
Galanin, a brain and pancreatic peptide with three receptor subtypes (GALR1, GALR2, and
GALR3), is hypothesized to participate in energy homeostasis and glucoregulation …
GALR3), is hypothesized to participate in energy homeostasis and glucoregulation …
Effect of dietary fatty acid composition on food intake, triglycerides, and hypothalamic peptides
JR Barson, O Karatayev, V Gaysinskaya, GQ Chang… - Regulatory peptides, 2012 - Elsevier
While a high-fat diet when compared to low-fat diet is known to produce overeating and
health complications, less is known about the effects produced by fat-rich diets differing in …
health complications, less is known about the effects produced by fat-rich diets differing in …
Neuropeptide modulation of addiction: Focus on galanin
SG Genders, KJ Scheller, E Djouma - Neuroscience & Biobehavioral …, 2020 - Elsevier
Addiction is a chronic, relapsing disorder characterised by the use of a substance or act to
the point of compulsion. There are a number of medical treatments available for the …
the point of compulsion. There are a number of medical treatments available for the …