A common feature of cancer cells is their ability to rewire their metabolism to sustain the
production of ATP and macromolecules needed for cell growth, division and survival. In …

Resveratrol (3, 4′, 5-trihy-droxystilbene), a natural phytoalexin polyphenol, exhibits anti-
oxidant, anti-inflammatory, and anti-carcinogenic properties. This phytoalexin is well …

With the advent of effective tools to study lipids, including mass spectrometry-based
lipidomics, lipids are emerging as central players in cancer biology. Lipids function as …

In tumorous tissues, the absence of vasculature supportive tissues intimates the formation of
leaky vessels and pores (100 nm to 2 μm in diameter) and the poor lymphatic system offers …

Abstract Cyclooxygenase‐2 (COX‐2) is frequently expressed in many types of cancers
exerting a pleiotropic and multifaceted role in genesis or promotion of carcinogenesis and …

Penile squamous cell carcinoma (PSCC) is a rare cancer with orphan disease designation
and a prevalence of 0.1–1 per 100,000 men in high-income countries, but it constitutes up to …

The peroxisome proliferator-activated receptor (PPAR) family includes three transcription
factors: PPARα, PPARβ/δ, and PPARγ. PPAR are nuclear receptors activated by oxidised …

Cancer immunotherapies that harness the body's immune system to combat tumors have
received extensive attention and become mainstream strategies for treating cancer. Despite …

The transport of specific molecules across lipid membranes is an essential function of all
living organisms. The processes are usually mediated by specific transporters. One of the …

Microtubule affinity regulating kinase (MARK4) is a potential drug target for different types of
cancer as it controls the early step of cell division. In this study, we have screened a series of …