Humans live in a 24-hour environment, in which light and darkness follow a diurnal pattern.
Our circadian pacemaker, the suprachiasmatic nuclei (SCN) in the hypothalamus, is …

Objective: This report surveys and evaluates the scientific research on evidence-based
healthcare design and extracts its implications for designing better and safer hospitals …

Objectives: To provide advice and guidance regarding the management of mood disorders,
derived from scientific evidence and supplemented by expert clinical consensus to formulate …

A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

Importance Bright light therapy is an evidence-based treatment for seasonal depression, but
there is limited evidence for its efficacy in nonseasonal major depressive disorder (MDD) …

Bright light therapy for seasonal affective disorder (SAD) has been investigated and applied
for over 20 years. Physicians and clinicians are increasingly confident that bright light …

A revision of the 2000 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken to …

Objective: Patients with bipolar disorder have recurrent major depression, residual mood
symptoms, and limited treatment options. Building on promising pilot data, the authors …

Context Major depressive disorder (MDD) in elderly individuals is prevalent and debilitating.
It is accompanied by circadian rhythm disturbances associated with impaired functioning of …

Light therapy'is established worldwide as the treatment of choice for seasonal affective
disorder. It is also successfuly used in nonseasonal depression, as well as for many other …