Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …
CRISPR-Cas-based antimicrobials: design, challenges, and bacterial mechanisms of resistance
A Mayorga-Ramos, J Zúñiga-Miranda… - ACS Infectious …, 2023 - ACS Publications
The emergence of antibiotic-resistant bacterial strains is a source of public health concern
across the globe. As the discovery of new conventional antibiotics has stalled significantly …
across the globe. As the discovery of new conventional antibiotics has stalled significantly …
The Challenge of overcoming antibiotic resistance in carbapenem-resistant Gram-negative bacteria:“Attack on Titan”
G Mancuso, S De Gaetano, A Midiri, S Zummo… - Microorganisms, 2023 - mdpi.com
The global burden of bacterial resistance remains one of the most serious public health
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …
concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients …
Biomaterials-mediated CRISPR/Cas9 delivery: recent challenges and opportunities in gene therapy
AK Dubey, E Mostafavi - Frontiers in Chemistry, 2023 - frontiersin.org
The use of biomaterials in delivering CRISPR/Cas9 for gene therapy in infectious diseases
holds tremendous potential. This innovative approach combines the advantages of …
holds tremendous potential. This innovative approach combines the advantages of …
Class 1 integrons and multiple mobile genetic elements in clinical isolates of the Klebsiella pneumoniae complex from a tertiary hospital in eastern China
L Wang, M Zhu, C Yan, Y Zhang, X He, L Wu… - Frontiers in …, 2023 - frontiersin.org
Background The emergence of highly drug-resistant K. pneumoniae, has become a major
public health challenge. In this work, we aim to investigate the diversity of species and …
public health challenge. In this work, we aim to investigate the diversity of species and …
Molecular Aspects of the Functioning of Pathogenic Bacteria Biofilm Based on Quorum Sensing (QS) Signal-Response System and Innovative Non-Antibiotic …
E Juszczuk-Kubiak - International Journal of Molecular Sciences, 2024 - mdpi.com
One of the key mechanisms enabling bacterial cells to create biofilms and regulate crucial
life functions in a global and highly synchronized way is a bacterial communication system …
life functions in a global and highly synchronized way is a bacterial communication system …
Updates on the Virulence Factors Produced by Multidrug-Resistant Enterobacterales and Strategies to Control Their Infections
MW Azam, R Zarrilli, AU Khan - Microorganisms, 2023 - mdpi.com
The Enterobacterales order is a massive group of Gram-negative bacteria comprised of
pathogenic and nonpathogenic members, including beneficial commensal gut microbiota …
pathogenic and nonpathogenic members, including beneficial commensal gut microbiota …
[HTML][HTML] Deciphering the genetics of antagonism and antimicrobial resistance in Bacillus velezensis HU-91 by whole genome analysis
Bacillus species are well reported plant growth promoting rhizobacteria which play an
important role in improving soil fertility, nutrient recycling, and controlling phytopathogens …
important role in improving soil fertility, nutrient recycling, and controlling phytopathogens …
Novel Dietary Approach with Probiotics, Prebiotics, and Synbiotics to Mitigate Antimicrobial Resistance and Subsequent Out Marketplace of Antimicrobial Agents: A …
HA Habteweld, T Asfaw - Infection and Drug Resistance, 2023 - Taylor & Francis
Antimicrobial resistance (AMR) is a significant public health concern worldwide. The
continuous use and misuse of antimicrobial agents have led to the emergence and spread …
continuous use and misuse of antimicrobial agents have led to the emergence and spread …
Antimicrobial resistance expansion in pathogens: a review of current mitigation strategies and advances towards innovative therapy
MA Adefisoye, AO Olaniran - JAC-Antimicrobial Resistance, 2023 - academic.oup.com
The escalating problem of antimicrobial resistance (AMR) proliferation in clinically important
pathogens has become one of the biggest threats to human health and the global economy …
pathogens has become one of the biggest threats to human health and the global economy …