Pancreatic diseases, a serious threat to human health, have garnered considerable
research interest, as they are associated with a high mortality rate. However, owing to the …

Pancreatic cancer is an aggressive malignancy with high mortality rates and poor
prognoses. Despite rapid progress in the diagnosis and treatment of pancreatic cancer, the …

Background and aim Subretinal fibrosis resulting from neovascular age-related macular
degeneration (nAMD) is one of the major causes of serious and irreversible vision loss …

Repair and reconstruction of critical-sized bone defects has always been a difficult task in
orthopedics. Hypoxia inducible factor-1α (HIF-1α) plays an important role in bone defect …

Umbilical cord‐mesenchymal stem cells (UC‐MSCs)‐derived exosomes have been
considered as an effective treatment for ischemic stroke. CircRNA BBS2 (circBBS2) was …

Background. Exosomes derived from cardiac microvascular endothelial cells (CMECs)
under hypoxia can mediate cardiac repair functions and alleviate pyroptosis and oxidative …

The method of 3D printing biotechnology for tissue engineering is widely used in repairing
and reconstructing bone defects, which remains a great challenge due to the lack of …

The concept of dedifferentiation and reprogramming of mature somatic cells holds much
promise for the three-front “war” against tissue damage, cancer, and aging. It was hoped that …

Recent evidence has demonstrated that mesenchymal stem cells (MSCs) can release a
large number of functionally specific microRNA (miRNA) microvesicles that play a role in …

Non-small-cell lung cancer (NSCLC) remains the leading cause of cancer-related death
worldwide. Accumulating researches have highlighted the ability of exosome-encapsulated …