The vegetative state and the minimally conscious state are disorders of consciousness that
can be acute and reversible or chronic and irreversible. Diffuse lesions of the thalami …

This essay complements the scientific and practice scope of the American Academy of
Neurology Guideline on Disorders of Consciousness by providing a discussion of the …

A survey of the emerging field of neuroethics that calls for a multidisciplinary, pragmatic
approach for tackling key issues and improving patient care. Today the measurable health …

Severe brain injury can leave patients with chronic disorders of consciousness. Because of
impaired responsiveness, many of these patients have traditionally been regarded as …

STUDY QUESTION Are patients willing to discuss the possibility of treatment being
unsuccessful as part of routine care offered at clinics, and what are the factors associated …

Physicians may employ the concept of medical futility to justify a decision not to pursue
certain treatments that may be requested or demanded by patients or surrogates. Medical …

Significant progress has been made in resuscitation science, with better chest compression,
use of automated defibrillators (1, 2), and in postresuscitation care with therapeutic …

Predicting neurological outcomes of neonates with acute brain injury is an essential
component of shared decision‐making, in order to guide the development of treatment goals …

Background Clinical studies, with a proper scientific design, on the impact of disclosing a
prognosis on a patient's psychological or physical conditions are rare. We investigated the …

Background Multiple sclerosis (MS) has a varied and uncertain trajectory. The recent
development of analytical processing tools that draw on large longitudinal patient databases …