[HTML][HTML] Barriers and facilitators to the participation of subjects in clinical trials: an overview of reviews

E Rodríguez-Torres, MM González-Pérez… - Contemporary clinical …, 2021 - Elsevier
Background The demand for clinical trial participants is today one of the highest it has ever
been and continues to increase. At the same time, subject recruitment continues to be …

The development of evidence-based European guidelines on the management of depression in palliative cancer care

L Rayner, A Price, M Hotopf, IJ Higginson - European journal of cancer, 2011 - Elsevier
Depression is common in cancer patients, particularly those with advanced disease. It is
associated with adverse outcomes such as increased pain, disability and poorer prognosis …

[HTML][HTML] Factors affecting patient participation in clinical trials in Ireland: a narrative review

E Walsh, A Sheridan - Contemporary Clinical Trials Communications, 2016 - Elsevier
Objective Clinical trials have long been considered the 'gold standard'of research generated
evidence in health care. Patient recruitment is an important determinant in the success of the …

Dying persons' perspectives on, or experiences of, participating in research: an integrative review

MJ Bloomer, AM Hutchinson, L Brooks… - Palliative …, 2018 - journals.sagepub.com
Background: Conducting research with dying persons can be controversial and challenging
due to concerns for the vulnerability of the dying and the potential burden on those who …

Patient, caregiver, health professional and researcher views and experiences of participating in research at the end of life: a critical interpretive synthesis of the …

MH Gysels, C Evans, IJ Higginson - BMC medical research methodology, 2012 - Springer
Background The development of the evidence-base informing end of life (EoL) care is
hampered by the assumption that patients at the EoL are too vulnerable to participate in …

[HTML][HTML] Family caregiver participation in palliative care research: challenging the myth

S Aoun, S Slatyer, K Deas, C Nekolaichuk - Journal of pain and symptom …, 2017 - Elsevier
Context Despite international guidelines emphasizing consumer-directed care and
autonomous decisions in research participation, there is a common myth that research can …

Conducting research interviews with bereaved family carers: when do we ask?

B Bentley, M O'Connor - Journal of palliative medicine, 2015 - liebertpub.com
Background: Interviews with bereaved family carers to examine the end-of-life experience of
the deceased are important tools for palliative care researchers, but the ethics of …

Overcoming recruitment challenges in palliative care clinical trials

TW LeBlanc, JE Lodato, DC Currow… - Journal of oncology …, 2013 - ascopubs.org
Purpose: Palliative care is increasingly viewed as a necessary component of cancer care,
especially for patients with advanced disease. Rigorous clinical trials are thus needed to …

[HTML][HTML] Reality of evidence-based practice in palliative care

C Visser, G Hadley, B Wee - Cancer biology & medicine, 2015 - ncbi.nlm.nih.gov
There has been a paradigm shift in medicine away from tradition, anecdote and theoretical
reasoning from the basic sciences towards evidence-based medicine (EBM). In palliative …

Why do patients with cancer die?

A Boire, K Burke, TR Cox, T Guise… - Nature Reviews …, 2024 - nature.com
Cancer is a major cause of global mortality, both in affluent countries and increasingly in
developing nations. Many patients with cancer experience reduced life expectancy and …