Blockade of chemo-resistance to 5-FU by a CK2-targeted combination via attenuating AhR-TLS-promoted genomic instability in human colon cancer cells

Z Wang, F Chen, Y Wang, S Gou - Toxicology and Applied Pharmacology, 2023 - Elsevier
As highly expressed in several human cancers, Casein Kinase 2 (CK2) is involved in
chemotherapy-induced resistance. As a new potent CK2 inhibitor, DN701 is used to …

[HTML][HTML] Exploring the pharmacological mechanism of Xianlian Jiedu decoction in the treatment of colorectal Cancer based on network pharmacology, molecular …

K Cai, XY Cao, F Chen, Y Zhu, DD Sun… - Pharmacological …, 2023 - Elsevier
Abstract Background Xianlian Jiedu Decoction (XLJDD) is a clinical effective prescription for
the treatment of colorectal cancer (CRC) for several decades. However, the effective …

A review on the pathogenesis theory of cancerous toxin from the viewpoint of system theory

T Guo, H Zhou, F Chen, Y Gu, L Li… - Science of Traditional …, 2024 - journals.lww.com
In recent years, traditional Chinese medicine (TCM) has made great progress in the
prevention and treatment of cancer. It has gradually revealed its characteristics and …