The 2022 World Health Organization classification of tumors of the urinary system and male genital organs—part B: prostate and urinary tract tumors

GJ Netto, MB Amin, DM Berney, EM Compérat, AJ Gill… - European urology, 2022 - Elsevier
Abstract The 2022 World Health Organization (WHO) classification of the urinary and male
genital tumors was recently published by the International Agency for Research on Cancer …

Secondary osteoporosis

PR Ebeling, HH Nguyen, J Aleksova… - Endocrine …, 2022 - academic.oup.com
Osteoporosis is a global public health problem, with fractures contributing to significant
morbidity and mortality. Although postmenopausal osteoporosis is most common, up to 30 …

Artificial intelligence for diagnosis and Gleason grading of prostate cancer: the PANDA challenge

W Bulten, K Kartasalo, PHC Chen, P Ström… - Nature medicine, 2022 - nature.com
Artificial intelligence (AI) has shown promise for diagnosing prostate cancer in biopsies.
However, results have been limited to individual studies, lacking validation in multinational …

Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative-intent surgery or radiotherapy (proPSMA): a prospective …

MS Hofman, N Lawrentschuk, RJ Francis, C Tang… - The Lancet, 2020 - thelancet.com
Background Conventional imaging using CT and bone scan has insufficient sensitivity when
staging men with high-risk localised prostate cancer. We aimed to investigate whether novel …

Prostate-only versus whole-pelvic radiation therapy in high-risk and very high-risk prostate cancer (POP-RT): outcomes from phase III randomized controlled trial

V Murthy, P Maitre, S Kannan, G Panigrahi… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE We report the clinical outcomes of a randomized trial comparing prophylactic
whole-pelvic nodal radiotherapy to prostate-only radiotherapy (PORT) in high-risk prostate …

Comparison of universal genetic testing vs guideline-directed targeted testing for patients with hereditary cancer syndrome

NJ Samadder, D Riegert-Johnson, L Boardman… - JAMA …, 2021 - jamanetwork.com
Importance Hereditary factors play a key role in the risk of developing several cancers.
Identification of a germline predisposition can have important implications for treatment …

The 2019 Genitourinary Pathology Society (GUPS) white paper on contemporary grading of prostate cancer

JI Epstein, MB Amin, SW Fine… - … of pathology & …, 2021 - meridian.allenpress.com
Context.—Controversies and uncertainty persist in prostate cancer grading. Objective.—To
update grading recommendations. Data Sources.—Critical review of the literature along with …

Molecular events in neuroendocrine prostate cancer development

Y Wang, Y Wang, X Ci, SYC Choi, F Crea, D Lin… - Nature Reviews …, 2021 - nature.com
Neuroendocrine prostate cancer (NEPC) is a lethal subtype of prostate cancer. NEPC arises
de novo only rarely; the disease predominantly develops from adenocarcinoma in response …

Patient-reported outcomes through 5 years for active surveillance, surgery, brachytherapy, or external beam radiation with or without androgen deprivation therapy for …

KE Hoffman, DF Penson, Z Zhao, LC Huang, R Conwill… - Jama, 2020 - jamanetwork.com
Importance Understanding adverse effects of contemporary treatment approaches for men
with favorable-risk and unfavorable-risk localized prostate cancer could inform treatment …

Molecular biomarkers in localized prostate cancer: ASCO guideline

SE Eggener, RB Rumble, AJ Armstrong… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE This guideline provides recommendations for available tissue-based prostate
cancer biomarkers geared toward patient selection for active surveillance, identification of …