[HTML][HTML] Ferroptosis: a new road towards cancer management

I Bano, P Horky, SQ Abbas, M Majid, AHM Bilal, F Ali… - Molecules, 2022 - mdpi.com
Ferroptosis is a recently described programmed cell death mechanism that is characterized
by the buildup of iron (Fe)-dependent lipid peroxides in cells and is morphologically …

[HTML][HTML] The dual role of ferroptosis in anthracycline-based chemotherapy includes reducing resistance and increasing toxicity

J Zhao, N Zhang, X Ma, M Li, H Feng - Cell Death Discovery, 2023 - nature.com
In conjunction with previous studies, we have noted that ferroptosis, as an emerging mode of
regulated cell death (RCD), is intimately related to anthracycline pharmacotherapy. Not only …

[HTML][HTML] Polyphyllin I suppresses the gastric cancer growth by promoting cancer cell ferroptosis

F Zheng, Y Wang, Q Zhang, Q Chen… - Frontiers in …, 2023 - frontiersin.org
Background: Ferroptosis is a new form of regulated cell death characterized by the
accumulation of iron-dependent lipid peroxides and membrane damages. Recent studies …

Novel pathways of fluoride-induced hepatotoxicity: P53-dependent ferroptosis induced by the SIRT1/FOXOs pathway and Nrf2/HO-1 pathway

D Wang, K Yin, Y Zhang, H Lu, L Hou, H Zhao… - … and Physiology Part C …, 2023 - Elsevier
Fluoride (F) is an environmental pollutant that continues to threaten human health. Long-
term or excessive fluoride exposure can cause a series of acute or chronic systemic and …

Implication of ferroptosis in hepatic toxicity upon single or combined exposure to polystyrene microplastics and cadmium

L Wang, X Zhang, M Xu, G Zheng, J Chen, S Li… - Environmental …, 2023 - Elsevier
Microplastics (MPs) are a newly emerging type of pollutants. To date, MPs have been found
in the atmosphere, soil, water, and even in human samples, posing a non-negligible threat …

[HTML][HTML] Prolyl 4-hydroxylase subunit beta (P4HB) could serve as a prognostic and radiosensitivity biomarker for prostate cancer patients

D Feng, L Li, D Li, R Wu, W Zhu, J Wang, L Ye… - European Journal of …, 2023 - Springer
Background Prolyl 4-hydroxylase subunit beta (P4HB) has been reported as a suppressor in
ferroptosis. However, no known empirical research has focused on exploring relationships …

HIF-1α Induced by Hypoxia promotes peripheral nerve Injury Recovery through regulating ferroptosis in DRG neuron

S An, J Shi, J Huang, Z Li, M Feng, G Cao - Molecular Neurobiology, 2024 - Springer
Peripheral nerve injury (PNI) usually has a poor effect on functional recovery and severely
declines the patient's quality of life. Our prior findings indicated that hypoxia remarkably …

FHOD1 is upregulated in glioma cells and attenuates ferroptosis of glioma cells by targeting HSPB1 signaling

F Zhang, L Wu, S Feng, Z Zhao, K Zhang… - CNS Neuroscience …, 2023 - Wiley Online Library
Background As a new type of regulatory cell death, ferroptosis has been proven to be
involved in cancer pathogenesis and therapeutic response. However, the detailed roles of …

Circular RNA SLC8A1 triggers hippocampal neuronal ferroptosis by regulating FUS-mediated ATF3 mRNA stability in epilepsy

Q Kang, J Zhang, C Xie, S Fang, W Chai - Experimental Cell Research, 2024 - Elsevier
Background Epilepsy is a neurological disorder characterized by recurrent seizures and is
often unresponsive to current treatment options. Ferroptosis, a recently defined iron …

NCI677397 targeting USP24mediated induction of lipid peroxidation induces ferroptosis in drugresistant cancer cells

SA Wang, YC Wu, FM Yang, FL Hsu… - Molecular …, 2023 - Wiley Online Library
Cancer represents a profound challenge to healthcare systems and individuals worldwide.
The development of multiple drug resistance is a major problem in cancer therapy and can …