Epithelial cells repress epithelial characteristics and elaborate mesenchymal characteristics
to migrate to other locations and acquire new properties. Epithelial plasticity responses are …

BMP signaling plays an important role in dentin development. BMPs and antagonists
regulate odontoblast differentiation and downstream gene expression via canonical Smad …

Childhood high-risk neuroblastomas with MYCN gene amplification are difficult to treat
effectively. This has focused attention on tumor-specific gene dependencies that underlie …

Harnessing the potential of human embryonic stem cells to mimic normal and aberrant
development with standardized models is a pressing challenge. Here we use micropattern …

We undertook a functional dissection of chromatin remodeler BAZ1B in neural crest (NC)
stem cells (NCSCs) from a uniquely informative cohort of typical and atypical patients …

Distraction osteogenesis is a bone-regenerative process in which an osteotomy is followed
by distraction of the surrounding vascularized bone segments, with formation of new bone …

Hox genes are an evolutionary highly conserved gene family. They determine the anterior-
posterior body axis in bilateral organisms and influence the developmental fate of cells …

Background Cannabinoids including cannabidiol have recognized genotoxic activities but
their significance has not been studied broadly epidemiologically across the teratological …

BMP signaling is one of the key pathways regulating craniofacial development. It is involved
in the early patterning of the head, the development of cranial neural crest cells, and facial …

Ribosomes are macromolecular machines that are globally required for the translation of all
proteins in all cells. Ribosome biogenesis, which is essential for cell growth, proliferation …