Abdominal aortic aneurysm: update on pathogenesis and medical treatments

J Golledge - Nature Reviews Cardiology, 2019 - nature.com
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in adults. Currently,
the only treatment for AAA is open or endovascular surgical repair. In most parts of the …

[HTML][HTML] AAA revisited: a comprehensive review of risk factors, management, and hallmarks of pathogenesis

V Kessler, J Klopf, W Eilenberg, C Neumayer… - Biomedicines, 2022 - mdpi.com
Despite declining incidence and mortality rates in many countries, the abdominal aortic
aneurysm (AAA) continues to represent a life-threatening cardiovascular condition with an …

[HTML][HTML] The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm

EL Chaikof, RL Dalman, MK Eskandari… - Journal of vascular …, 2018 - Elsevier
Background Decision-making related to the care of patients with an abdominal aortic
aneurysm (AAA) is complex. Aneurysms present with varying risks of rupture, and patient …

Ruptured abdominal aortic aneurysm—epidemiology, predisposing factors, and biology

T Schmitz-Rixen, M Keese, M Hakimi, A Peters… - … archives of surgery, 2016 - Springer
Purpose Abdominal aortic aneurysm is a common degenerative vascular disorder
associated with sudden death due to aortic rupture. This review describes epidemiology …

[HTML][HTML] Intraluminal thrombus: Innocent bystander or factor in abdominal aortic aneurysm pathogenesis?

AJ Boyd - JVS-Vascular Science, 2021 - Elsevier
Abstract Background Abdominal aortic aneurysms (AAAs) represent a complex multifactorial
hemodynamic, thrombotic, and inflammatory process that can ultimately result in aortic …

Role of intraluminal thrombus in abdominal aortic aneurysm ruptures: A hemodynamic point of view

Y Qiu, Y Wang, Y Fan, L Peng, R Liu, J Zhao… - Medical …, 2019 - Wiley Online Library
Purpose Intraluminal thrombus (ILTs) are found in most abdominal aortic aneurysms (AAAs)
of clinically relevant size; however, the role of ILTs in AAA ruptures remains unclear. This …

[HTML][HTML] Low-dose aspirin and rupture of abdominal aortic aneurysm

H Wemmelund, TMM Jørgensen, A Høgh… - Journal of Vascular …, 2017 - Elsevier
Objective The use of low-dose aspirin (acetylsalicylic acid [ASA]) has been suggested to
attenuate growth of abdominal aortic aneurysms (AAAs), yet solid clinical evidence of this …

[HTML][HTML] The–not so–solid 5.5 cm threshold for abdominal aortic aneurysm repair: facts, misinterpretations, and future directions

N Kontopodis, D Pantidis, A Dedes, N Daskalakis… - Frontiers in …, 2016 - frontiersin.org
Abdominal aortic aneurysms (AAAs) represent a focal dilation of the aorta exceeding 1.5
times its normal diameter. It is reported that 4–8% of men and 0.5–1% of women above 50 …

Finite element analysis of abdominal aortic aneurysms: predicted rupture risk correlates with aortic wall histology in individual patients

P Erhart, C Grond-Ginsbach, M Hakimi… - Journal of …, 2014 - journals.sagepub.com
Purpose: To evaluate a finite element analysis (FEA) model as a predictive tool for
abdominal aortic aneurysm (AAA) rupture risk assessment. Methods: FEA of asymptomatic …

[HTML][HTML] Gender, smoking, body size, and aneurysm geometry influence the biomechanical rupture risk of abdominal aortic aneurysms as estimated by finite element …

ML Liljeqvist, R Hultgren, A Siika, TC Gasser… - Journal of vascular …, 2017 - Elsevier
Objective Finite element analysis (FEA) has been suggested to be superior to maximal
diameter measurements in predicting rupture of abdominal aortic aneurysms (AAAs). Our …