Limitations associated with conventional bone substitutes such as autografts, increasing
demand for bone grafts, and growing elderly population worldwide necessitate development …

Osteoarthritis (OA) is a chronic disease that causes pain and disability in adults, affecting≈
300 million people worldwide. It is caused by damage to cartilage, including cellular …

The fast-developing field of 3D bio-printing has been extensively used to improve the
usability and performance of scaffolds filled with cells. Over the last few decades, a variety of …

Along with the rapid and extensive advancements in the 3D printing field, a diverse range of
uses for 3D printing have appeared in the spectrum of medical applications. Vat …

Bone generally displays a high intrinsic capacity to regenerate. Nonetheless, large osseous
defects sometimes fail to heal. The treatment of such large segmental defects still represents …

This paper gives a detailed analysis of nanotechnology's rising involvement in numerous
surgical fields. We investigate the use of nanotechnology in orthopedic surgery …

This study aims to explore the effects of various hydroxyapatite (HA) doping techniques in
depth. For this purpose, two ions with comparable sizes, namely Mn 2+ and Cu 2+, were …

Nanohydroxyapatite (nanoHAP) is widely used in bone regeneration, but there is a need to
enhance its properties to provide stimuli for cell commitment and osteoconduction. This …

There is a high incidence of fractures in clinical practice and therapy. The repairment of
critical size defects in the skeletal system remains a huge challenge for surgeons and …

Scaffolds having appropriate mechanical strength and providing a proper microenvironment
for osteogenesis are expected to be effective alternatives to autografts for bone …