The CNS critically relies on the formation and proper function of its vasculature during
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …

Simple Summary Despite the continuous development of treatment technology,
glioblastoma remains a challenge for modern medicine. The standard of care remains a …

The second near-infrared (NIR-II, 1000–1700 nm) fluorescent probes have significant
advantages over visible or NIR-I (600–900 nm) imaging for both depth of penetration and …

Simple Summary This paper summarizes the crosstalk between tumor/non-tumor cells and
other elements of the glioblastoma (GB) microenvironment. In tumor pathology, glial cells …

Differential diagnosis of brain lesion pathologies is complex, but it is nevertheless crucial for
appropriate clinical management. Advanced imaging methods, including diffusion-weighted …

MicroRNAs (miRNA) are small non-coding RNAs that are 20–23 nucleotides in length,
functioning as regulators of oncogenes or tumor suppressor genes. They are molecular …

Glioblastoma multiforme, the deadliest primary brain tumor, is characterized by an excessive
and aberrant neovascularization. The initial expectations raised by anti-angiogenic drugs …

Tumor growth depends on the vascular system, either through the expansion of blood
vessels or novel adaptation by tumor cells. One of these novel pathways is vasculogenic …

Simple Summary PCNA is an interesting target for cancertreatment due to its essential
activities in DNA replication and repair and its recently discovered regulatory roles in cellular …

Blood vessels are a key target for cancer therapy. Compared with the healthy vasculature,
tumor blood vessels are extremely immature, highly permeable, and deficient in pericytes …