The emergence and influence of internal states

SW Flavell, N Gogolla, M Lovett-Barron, M Zelikowsky - Neuron, 2022 - cell.com
Animal behavior is shaped by a variety of" internal states"—partially hidden variables that
profoundly shape perception, cognition, and action. The neural basis of internal states, such …

Visual processing in the fly, from photoreceptors to behavior

TA Currier, MM Pang, TR Clandinin - Genetics, 2023 - academic.oup.com
Originally a genetic model organism, the experimental use of Drosophila melanogaster has
grown to include quantitative behavioral analyses, sophisticated perturbations of neuronal …

The spatial and temporal structure of neural activity across the fly brain

ES Schaffer, N Mishra, MR Whiteway, W Li… - Nature …, 2023 - nature.com
What are the spatial and temporal scales of brainwide neuronal activity? We used swept,
confocally-aligned planar excitation (SCAPE) microscopy to image all cells in a large …

Global change in brain state during spontaneous and forced walk in Drosophila is composed of combined activity patterns of different neuron classes

S Aimon, KY Cheng, J Gjorgjieva, ICG Kadow - Elife, 2023 - elifesciences.org
Movement-correlated brain activity has been found across species and brain regions. Here,
we used fast whole brain lightfield imaging in adult Drosophila to investigate the relationship …

Transforming descending input into behavior: The organization of premotor circuits in the Drosophila Male Adult Nerve Cord connectome

HSJ Cheong, K Eichler, T Stürner, SK Asinof… - bioRxiv, 2023 - biorxiv.org
In most animals, a relatively small number of descending neurons (DNs) connect higher
brain centers in the animal's head to circuits and motor neurons (MNs) in the nerve cord of …

[HTML][HTML] Synaptic gradients transform object location to action

M Dombrovski, MY Peek, JY Park, A Vaccari… - Nature, 2023 - nature.com
To survive, animals must convert sensory information into appropriate behaviours,. Vision is
a common sense for locating ethologically relevant stimuli and guiding motor responses …

Descending neuron population dynamics during odor-evoked and spontaneous limb-dependent behaviors

F Aymanns, CL Chen, P Ramdya - Elife, 2022 - elifesciences.org
Deciphering how the brain regulates motor circuits to control complex behaviors is an
important, long-standing challenge in neuroscience. In the fly, Drosophila melanogaster, this …

Descending control and regulation of spontaneous flight turns in Drosophila

IG Ros, JJ Omoto, MH Dickinson - Current Biology, 2024 - cell.com
The clumped distribution of resources in the world has influenced the pattern of foraging
behavior since the origins of locomotion, selecting for a common search motif in which …

Neural Circuits Underlying Behavioral Flexibility: Insights From Drosophila

AV Devineni, KM Scaplen - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
Behavioral flexibility is critical to survival. Animals must adapt their behavioral responses
based on changes in the environmental context, internal state, or experience. Studies in …

Two brain pathways initiate distinct forward walking programs in Drosophila

SS Bidaye, M Laturney, AK Chang, Y Liu, T Bockemühl… - Neuron, 2020 - cell.com
An animal at rest or engaged in stationary behaviors can instantaneously initiate goal-
directed walking. How descending brain inputs trigger rapid transitions from a non-walking …