[HTML][HTML] Sex differences in mechanisms of pain hypersensitivity
The introduction of sex-as-a-biological-variable policies at funding agencies around the
world has led to an explosion of very recent observations of sex differences in the biology …
world has led to an explosion of very recent observations of sex differences in the biology …
Methods for studying P2X4 receptor ion channels in immune cells
The P2X4 receptor is a trimeric ligand-gated ion channel activated by adenosine 5′-
triphosphate (ATP). P2X4 is present in immune cells with emerging roles in inflammation …
triphosphate (ATP). P2X4 is present in immune cells with emerging roles in inflammation …
[HTML][HTML] Spinal neuronal activity and neuroinflammatory component in a mouse model of CFA-induced vestibulodynia
S Boccella, M Perrone, A Fusco, R Bonsale… - Brain, Behavior, and …, 2024 - Elsevier
Vestibulodynia is a complex pain disorder characterized by chronic discomfort in the vulvar
region, often accompanied by tactile allodynia and spontaneous pain. In patients a …
region, often accompanied by tactile allodynia and spontaneous pain. In patients a …
Sexually dimorphic effects of pexidartinib on nerve injury‐induced neuropathic pain in mice
F Saika, Y Fukazawa, Y Hatano, S Kishioka, Y Hino… - Glia, 2024 - Wiley Online Library
It is well‐established that spinal microglia and peripheral macrophages play critical roles in
the etiology of neuropathic pain; however, growing evidence suggests sex differences in …
the etiology of neuropathic pain; however, growing evidence suggests sex differences in …
[HTML][HTML] P2X4 signalling contributes to hyperactivity but not pain sensitization comorbidity in a mouse model of attention deficit/hyperactivity disorder
S Bou Sader Nehme, S Sanchez-Sarasua… - Frontiers in …, 2024 - frontiersin.org
Introduction: Attention deficit/hyperactivity disorder (ADHD) is a common
neurodevelopmental disorder characterized by hyperactivity, inattention, and impulsivity that …
neurodevelopmental disorder characterized by hyperactivity, inattention, and impulsivity that …
[HTML][HTML] Daphnetin Ameliorates Neuropathic Pain via Regulation of Microglial Responses and Glycerophospholipid Metabolism in the Spinal Cord
W Liang, T Zhang, M Zhang, J Gao, R Huang… - Pharmaceuticals, 2024 - mdpi.com
Neuropathic pain (NP) is a common type of chronic pain caused by a lesion or disease of
the somatosensory nervous system. This condition imposes a considerable economic …
the somatosensory nervous system. This condition imposes a considerable economic …
Exploring the role of P2X receptors in age-related macular degeneration
S Youn - 2024 - open.library.ubc.ca
Purinergic signaling via ATP-activated P2X receptors has been studied in age-related
macular degeneration (AMD), where retinal pigment epithelium (RPE) cells release ATP and …
macular degeneration (AMD), where retinal pigment epithelium (RPE) cells release ATP and …