Inflammation is a complex biological response fundamental to how the body deals with
injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a …

Mast cells are best recognized for their role in allergy and anaphylaxis, but increasing
evidence supports their role in neurogenic inflammation leading to pain and itch. Mast cells …

The skin, including the hypodermis, is the largest body organ and is in constant contact with
the environment. Neurogenic inflammation is the result of the activity of nerve endings and …

Fibromyalgia is one of the most important “rheumatic” disorders, after osteoarthritis. The
etiology of the disease is still not clear. At the moment, the most defined pathological …

Pain is an unpleasant sensation associated with injury, inflammation, and infection. It has
been demonstrated that communication between immune cells and neurons plays a vital …

Degranulation of meningeal mast cells leading to the sensitization of trigeminal vascular
afferent processing is believed to be one of the mechanisms underlying the migraine pain …

Mast cells (MCs) are immune cells and are widely distributed throughout the body. MCs are
not only classically viewed as effector cells of some allergic diseases but also participate in …

This paper is the fortieth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Various plant species from the Litsea genus have been claimed to be beneficial for pain
relief. The PRISMA approach was adopted to identify studies that reported analgesic …

Introduction Feline idiopathic cystitis is a common, chronic-relapsing disorder of the lower
urinary tract. In addition to environmental modification/enrichment, long-term and safe …