Plants in anticancer drug discovery: from molecular mechanism to chemoprevention

AJ Siddiqui, S Jahan, R Singh, J Saxena… - BioMed Research …, 2022 - Wiley Online Library
Cancer is one of the primary causes of mortality globally, and the discovery of new
anticancer drugs is the most important need in recent times. Natural products have been …

Apoptotic or antiproliferative activity of natural products against keratinocytes for the treatment of psoriasis

TH Huang, CF Lin, A Alalaiwe, SC Yang… - International Journal of …, 2019 - mdpi.com
Natural products or herbs can be used as an effective therapy for treating psoriasis, an
autoimmune skin disease that involves keratinocyte overproliferation. It has been …

Bakuchiol–a natural meroterpenoid: structure, isolation, synthesis and functionalization approaches

TPA Krishna, B Edachery, S Athalathil - RSC advances, 2022 - pubs.rsc.org
Bakuchiol is an emblematic meroterpene class of natural product extracted from Psoralea
corylifolia. It has been reported to possess a broad range of biological and pharmacological …

Plants-derived biomolecules as potent antiviral phytomedicines: new insights on ethnobotanical evidences against coronaviruses

AJ Siddiqui, C Danciu, SA Ashraf, A Moin, R Singh… - Plants, 2020 - mdpi.com
SARS-CoV-2 infection (COVID-19) is in focus over all known human diseases, because it is
destroying the world economy and social life, with increased mortality rate each day. To …

Potential energy surface, effect of solvents in molecular level, experimental spectra (FTIR, Raman, UV–visible & NMR), electronic, and dynamics simulation of …

N Mani, D Nicksonsebastin, M Prasath… - Journal of Molecular …, 2023 - Elsevier
The spectroscopic characteristics, molecular structure, and biological characteristics of the
Isobavachalcone (IBC) structure have been studied using computational techniques utilizing …

[HTML][HTML] Bavachin attenuates LPS-induced inflammatory response and inhibits the activation of NLRP3 inflammasome in macrophages

YL Hung, SC Wang, K Suzuki, SH Fang, CS Chen… - Phytomedicine, 2019 - Elsevier
Background Bavachin is a natural product isolated from Psoralea corylifolia L. that has been
applied as a traditional medicine in Asian countries. However, the anti-inflammatory effects …

Genus Psoralea: A review of the traditional and modern uses, phytochemistry and pharmacology

B Koul, P Taak, A Kumar, A Kumar, I Sanyal - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance The genus Psoralea (Fabaceae) harbours 105
accepted species that are extensively used by local peoples and medicinal practitioners of …

Anti-tyrosinase and antioxidant activity of meroterpene bakuchiol from Psoralea corylifolia (L.)

A Cariola, M El Chami, J Granatieri, L Valgimigli - Food Chemistry, 2023 - Elsevier
Bakuchiol is gaining major interest for treatments against skin photoaging. The kinetics of
mushroom tyrosinase inhibition by bakuchiol, by real-time oxygen sensing and UV–vis …

Review of medicinal plants and active pharmaceutical ingredients against aquatic pathogenic viruses

W Liao, L Huang, S Han, D Hu, Y Xu, M Liu, Q Yu… - Viruses, 2022 - mdpi.com
Aquaculture offers a promising source of economic and healthy protein for human
consumption, which can improve wellbeing. Viral diseases are the most serious type of …

Induction of G2/M Cell Cycle Arrest via p38/p21Waf1/Cip1-Dependent Signaling Pathway Activation by Bavachinin in Non-Small-Cell Lung Cancer Cells

JT Pai, MW Hsu, YL Leu, KT Chang, MS Weng - Molecules, 2021 - mdpi.com
Lung cancer is the most commonly diagnosed malignant cancer in the world. Non-small-cell
lung cancer (NSCLC) is the major category of lung cancer. Although effective therapies have …