Neurodegenerative diseases, such as Alzheimer's disease (AD), are characterized by
massive loss of specific neurons. It is a progressive disabling, severe and fatal complex …

CAD (Carbamoyl-phosphate synthetase 2, Aspartate transcarbamoylase, and
Dihydroorotase) is a multifunctional protein that participates in the initial three speed-limiting …

Rivastigmine, a reversible cholinesterase inhibitor, is frequently indicated in the
management of demented conditions associated with Alzheimer disease. The major hurdle …

Pyrimidine‐based derivatives have attracted a lot of interest in heterocyclic chemistry due to
its versatile structure and diverse biological activities. This study provides a comprehensive …

Thiourea and its derivatives have become a significant focal point within the organic
synthesis field, garnering attention for their diverse biological applications, including …

Rivastigmine, a reversible cholinesterase inhibitor, is frequently indicated in the
management of demented conditions associated with Alzheimer disease. The major hurdle …

Herein, we report the use of the readily available and bench-stable pyrimidinyl sulfones as
electrophiles in Ni-catalyzed Suzuki− Miyaura cross-coupling reactions. This method allows …

Background: Alzheimer's disease is a neurological dysfunction of the brain caused by
neurodegeneration and oxidative stress. Some viruses, such as herpes viruses, HSV-1, and …

The reactivity of four 4‐pyrimidyl sulfonic esters in Palladium‐catalyzed Suzuki–Miyaura
cross‐coupling reactions was studied with various boronic acids. All the reactions were …

The series of new pyrimidine derivatives 6-substituted-5-cyano-4-(P-phenyl-4H) Pyrimidine
and Substituted thieno [2, 3-d] Pyrimidine were synthesized by the reaction between some …