[HTML][HTML] Vagus nerve stimulation as a potential therapy in early Alzheimer's disease: A review

M Vargas-Caballero, H Warming, R Walker… - Frontiers in human …, 2022 - frontiersin.org
Cognitive dysfunction in Alzheimer's disease (AD) is caused by disturbances in neuronal
circuits of the brain underpinned by synapse loss, neuronal dysfunction and neuronal death …

The future of brain circuit-targeted therapeutics

SH Siddiqi, S Khosravani, JD Rolston… - …, 2024 - nature.com
The principle of targeting brain circuits has drawn increasing attention with the growth of
brain stimulation treatments such as transcranial magnetic stimulation (TMS), deep brain …

[HTML][HTML] Implantable pulse generators for deep brain stimulation: challenges, complications, and strategies for practicality and longevity

C Sarica, C Iorio-Morin, DH Aguirre-Padilla… - Frontiers in Human …, 2021 - frontiersin.org
Deep brain stimulation (DBS) represents an important treatment modality for movement
disorders and other circuitopathies. Despite their miniaturization and increasing …

Concurrent stimulation and sensing in bi-directional brain interfaces: a multi-site translational experience

J Ansó, M Benjaber, B Parks, S Parker… - Journal of neural …, 2022 - iopscience.iop.org
Objective. To provide a design analysis and guidance framework for the implementation of
concurrent stimulation and sensing during adaptive deep brain stimulation (aDBS) with …

Focal cortex stimulation with a novel implantable device and antiseizure outcomes in 2 prospective multicenter single-arm trials

A Schulze-Bonhage, M Hirsch, S Knake… - JAMA …, 2023 - jamanetwork.com
Importance For the large population of people with drug-refractory epilepsy, alternative
treatment approaches are needed. Clinical trial outcomes of a novel stimulation device …

NeuralTree: A 256-channel 0.227-μJ/class versatile neural activity classification and closed-loop neuromodulation SoC

U Shin, C Ding, B Zhu, Y Vyza… - IEEE Journal of Solid …, 2022 - ieeexplore.ieee.org
Closed-loop neural interfaces with on-chip machine learning can detect and suppress
disease symptoms in neurological disorders or restore lost functions in paralyzed patients …

[HTML][HTML] Neural interface systems with on-device computing: Machine learning and neuromorphic architectures

J Yoo, M Shoaran - Current opinion in biotechnology, 2021 - Elsevier
Highlights•Neural interfaces continue to improve in channel count and form factor.•Low-
power machine learning and neuromorphic processors can be integrated onto neural …

Closed-loop neural prostheses with on-chip intelligence: A review and a low-latency machine learning model for brain state detection

B Zhu, U Shin, M Shoaran - IEEE transactions on biomedical …, 2021 - ieeexplore.ieee.org
The application of closed-loop approaches in systems neuroscience and therapeutic
stimulation holds great promise for revolutionizing our understanding of the brain and for …

Wearable devices for seizure detection: Practical experiences and recommendations from the Wearables for Epilepsy And Research (WEAR) International Study …

E Bruno, S Böttcher, PF Viana, M Amengual‐Gual… - …, 2021 - Wiley Online Library
Abstract The Wearables for Epilepsy And Research (WEAR) International Study Group
identified a set of methodology standards to guide research on wearable devices for seizure …

[HTML][HTML] Transcutaneous auricular vagus nerve stimulation induces stabilizing modifications in large-scale functional brain networks: towards understanding the effects …

R von Wrede, T Rings, S Schach, C Helmstaedter… - Scientific reports, 2021 - nature.com
Transcutaneous auricular vagus nerve stimulation (taVNS) is a novel non-invasive brain
stimulation technique considered as a potential supplementary treatment option for subjects …