Around the EQUATOR with Clin‐STAR: Prediction modeling opportunities and challenges in aging research

WJ Deardorff, LG Diaz‐Ramirez… - Journal of the …, 2024 - Wiley Online Library
Abstract The 2015 Transparent Reporting of a multivariable prediction model for Individual
Prognosis Or Diagnosis (TRIPOD) Statement was published to improve reporting …

[HTML][HTML] Pathologic correlates of aging-related tau astrogliopathy: ARTAG is associated with LATE-NC and cerebrovascular pathologies, but not with ADNC

Y Katsumata, X Wu, KZ Aung, K Gauthreaux… - Neurobiology of …, 2024 - Elsevier
Age-related tau astrogliopathy (ARTAG) is detectable in the brains of over one-third of
autopsied persons beyond age 80, but the pathoetiology of ARTAG is poorly understood …

Comprehensive assessment of TDP-43 neuropathology data in the National Alzheimer's Coordinating Center database

DC Woodworth, KM Nguyen, L Sordo… - Acta …, 2024 - Springer
TDP-43 proteinopathy is a salient neuropathologic feature in a subset of frontotemporal
lobar degeneration (FTLD-TDP), in amyotrophic lateral sclerosis (ALS-TDP), and in limbic …

Traumatic Brain Injury, Seizures, and Cognitive Impairment Among Older Adults

Y Zhu, J Williams, K Beyene, JF Trani… - JAMA Network …, 2024 - jamanetwork.com
Importance Traumatic brain injury (TBI), seizures, and dementia increase with age. There is
a gap in understanding the associations of TBI, seizures, and medications such as …

Extracellular Vesicles for Alzheimer Disease and Dementia Diagnosis

HB Taha - medRxiv, 2024 - medrxiv.org
Accurate differential diagnosis of dementia disorders including Alzheimer disease (AD),
frontotemporal dementia (FTD), dementia with Lewy bodies (DLB), Parkinson disease …

Associations between dementia staging, neuropsychiatric behavioral symptoms, and divorce or separation in late life: A case control study

JK Monin, G McAvay, E Zang, B Vander Wyk… - PLoS one, 2023 - journals.plos.org
Dementia can be difficult for married couples for many reasons, including the introduction of
caregiving burden, loss of intimacy, and financial strain. In this study, we investigated the …

Depression, vascular burden, and dementia prevalence in late middle-aged and older Black adults

SA Levy, MB Misiura, JG Grant… - The Journals of …, 2024 - academic.oup.com
Objectives Late-life depression and white matter hyperintensities (WMH) have been linked
to increased dementia risk. However, there is a dearth of literature examining these …

Sleep Disorders and Cognitive Aging Among Cognitively Impaired Versus Unimpaired Older Adults

S Lee, ME Nelson, F Hamada, ML Wallace… - The …, 2024 - academic.oup.com
Abstract Background and Objectives Sleep disorders often predict or co-occur with cognitive
decline. Yet, little is known about how the relationship unfolds among older adults at risk for …

Recruiting a prospective community cohort to study Alzheimer's disease and structural and social determinants of health among adults racialized as Black: The …

AIB Walker, JF Trani, CF Banks… - … Research & Clinical …, 2024 - Wiley Online Library
INTRODUCTION This ongoing, prospective study examines the effectiveness of methods
used to successfully recruit and retain 238 Black older adults in a longitudinal, observational …

Development and Validity of Norms for Cognitive Dispersion on the Uniform Data Set 3.0 Neuropsychological Battery

AM Kiselica, AN Kaser, DS Weitzner… - Archives of Clinical …, 2024 - academic.oup.com
Objective Cognitive dispersion indexes intraindividual variability in performance across a
battery of neuropsychological tests. Measures of dispersion show promise as markers of …