Sp1 and Sp3 are oxidative stress-inducible, antideath transcription factors in cortical neurons

H Ryu, J Lee, K Zaman, J Kubilis… - Journal of …, 2003 - Soc Neuroscience
Neuronal cell death in response to oxidative stress may reflect the failure of endogenous
adaptive mechanisms. However, the transcriptional activators induced by oxidative stress in …

DNA double-strand break repair: a theoretical framework and its application

PJ Murray, B Cornelissen… - Journal of The …, 2016 - royalsocietypublishing.org
DNA double-strand breaks (DSBs) are formed as a result of genotoxic insults, such as
exogenous ionizing radiation, and are among the most serious types of DNA damage. One …

Dose response and kinetics of foci disappearance following exposure to high-and low-LET ionizing radiation

R Ugenskiene, K Prise, M Folkard, J Lekki… - … journal of radiation …, 2009 - Taylor & Francis
Purpose: The effect of different radiation qualities on (i) 53BP1 (p53 Binding Protein 1) and p-
ATM (phosphorylated ataxia telangiectasia mutated) foci induction, and (ii) on the kinetics of …

p21+/+ (CDKN1A+/+) and p21–/– (CDKN1A–/–) Human Colorectal Carcinoma Cells Display Equivalent Amounts of Thermal Radiosensitization

C Larsson, CE Ng - Radiation research, 2003 - meridian.allenpress.com
Abstract Larsson, CL and Ng, CE p21+/+(CDKN1A+/+) and p21–/–(CDKN1A–/–) Human
Colorectal Carcinoma Cells Display Equivalent Amounts of Thermal Radiosensitization …

Comparison of apoptotic, necrotic and clonogenic cell death and inhibition of cell growth following camptothecin and X-radiation treatment in a human melanoma and …

SS Qutob, CE Ng - Cancer chemotherapy and pharmacology, 2002 - Springer
Purpose: We evaluated apoptotic, necrotic and clonogenic cell death and inhibition of cell
growth in a human melanoma cell line (Sk-Mel-3) and a normal human fibroblast cell line …

Oxygenation and radiosensitization consequences of solid tumour perfusion

B Wadsworth - 2020 - open.library.ubc.ca
Solid tumours often develop regions that are poorly oxygenated (hypoxic). Hypoxic tumour
cells are resistant to radiation and are associated with poor patient outcome.“Chronic …