Recent advances in nanotechnology have generated wide interest in applying
nanomaterials for neural prostheses. An ideal neural interface should create seamless …

The repair of wounds is one of the most complex biological processes that occur during
human life. After an injury, multiple biological pathways immediately become activated and …

Injury to the central nervous system (CNS) alters the molecular and cellular composition of
neural tissue and leads to glial scarring, which inhibits the regrowth of damaged axons …

Chronically implanted recording electrode arrays linked to prosthetics have the potential to
make positive impacts on patients suffering from full or partial paralysis. Such arrays are …

Spinal cord injury (SCI) is a severe neurological disease; however, there is no effective
treatment for spinal cord injury. Neuroinflammation involves the activation of resident …

Tumors of glial origin consist of a core mass and a penumbra of invasive, single cells,
decreasing in numbers towards the periphery and still detectable several centimeters away …

Acute ischaemic stroke accounts for 6.5 million deaths per year, and by 2030 will result in
the annual loss of over 200 million disability-adjusted life years globally. There have been …

Following CNS injury, in an apparently counterintuitive response, scar tissue formation
inhibits axonal growth, imposing a major barrier to regeneration. Accordingly, scar …

Inflammatory reaction following a spinal cord injury (SCI) contributes substantially to
secondary effects, with both beneficial and devastating effects. This review summarizes the …

Reactive astrogliosis is a pathologic hallmark of spinal cord injury (SCI). It is characterised
by profound morphological, molecular, and functional changes in astrocytes that occur …