Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair

W Cai, T Yang, H Liu, L Han, K Zhang, X Hu… - Progress in …, 2018 - Elsevier
Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-
modulated transcription factor that governs the expression of genes involved in …

Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients.

A Retter, D Wyncoll, R Pearse… - British journal of …, 2013 - search.ebscohost.com
The article offers information on the management of anaemia and red cell transfusion in
adult critically ill patients. It states that erythropoietin should not be used to treat anaemia in …

[PDF][PDF] Human albumin: old, new, and emerging applications

J Rozga, T Piątek, P Małkowski - Ann Transplant, 2013 - ppm.wum.edu.pl
Human serum albumin has been widely used in an array of clinical settings for nearly 7
decades. Although there is no evidence to support the use of albumin rather than crystalloid …

Traditional systolic blood pressure targets underestimate hypotension-induced secondary brain injury

M Brenner, DM Stein, PF Hu, B Aarabi… - Journal of Trauma …, 2012 - journals.lww.com
BACKGROUND: Vital signs, particularly blood pressure, are often manipulated to maximize
perfusion and optimize recovery from severe traumatic brain injury (sTBI). We investigated …

[HTML][HTML] Acute respiratory distress syndrome in traumatic brain injury: how do we manage it?

V Della Torre, R Badenes, F Corradi… - Journal of thoracic …, 2017 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) is an important cause of morbidity and mortality worldwide. TBI
patients frequently suffer from lung complications and acute respiratory distress syndrome …

Impact of non-neurological complications in severe traumatic brain injury outcome

L Corral, CF Javierre, JL Ventura, P Marcos, JI Herrero… - Critical care, 2012 - Springer
Introduction Non-neurological complications in patients with severe traumatic brain injury
(TBI) are frequent, worsening the prognosis, but the pathophysiology of systemic …

Lack of recovery in monocyte human leukocyte antigen-DR expression is independently associated with the development of sepsis after major trauma

A Cheron, B Floccard, B Allaouchiche, C Guignant… - Critical Care, 2010 - Springer
Introduction Major trauma is characterized by an overwhelming pro-inflammatory response
and an accompanying anti-inflammatory response that lead to a state of …

Relevance of albumin in modern critical care medicine

JL Vincent - Best practice & research Clinical anaesthesiology, 2009 - Elsevier
The relevance of albumin administration in the critical care setting remains controversial. We
know that albumin has numerous important physiological effects and many potentially …

Anemia and brain oxygen after severe traumatic brain injury

M Oddo, JM Levine, M Kumar, K Iglesias… - Intensive care …, 2012 - Springer
Purpose To investigate the relationship between hemoglobin (Hgb) and brain tissue oxygen
tension (PbtO 2) after severe traumatic brain injury (TBI) and to examine its impact on …

Septic encephalopathy

M Ziaja - Current neurology and neuroscience reports, 2013 - Springer
Every year, more cases of sepsis appear in intensive care units. The most frequent
complication of sepsis is septic encephalopathy (SE), which is also the essential …