Improved primary staging of marginal-zone lymphoma by addition of CXCR4-directed PET/CT

J Duell, F Krummenast, A Schirbel… - Journal of Nuclear …, 2021 - Soc Nuclear Med
PET/CT with 18F-FDG is an integral component in the primary staging of most lymphomas.
However, its utility is limited in marginal-zone lymphoma (MZL) because of inconsistent 18F …

The use of the macrocyclic chelator DOTA in radiochemical separations

Z Baranyai, G Tircsó, F Rösch - European Journal of Inorganic …, 2020 - Wiley Online Library
Radiometals play an important role in the diagnosis of physiological processes in vivo by
means of imaging technologies, but also increasingly contribute to the treatment of diseases …

Cell tracking in cancer immunotherapy

J Perrin, M Capitao, M Mougin-Degraef… - Frontiers in …, 2020 - frontiersin.org
The impressive development of cancer immunotherapy in the last few years originates from
a more precise understanding of control mechanisms in the immune system leading to the …

Clinical advances and perspectives in targeted radionuclide therapy

N Lepareur, B Ramée, M Mougin-Degraef… - Pharmaceutics, 2023 - mdpi.com
Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …

CXCR4-directed imaging in solid tumors

RA Werner, S Kircher, T Higuchi, M Kircher… - Frontiers in …, 2019 - frontiersin.org
Despite histological evidence in various solid tumor entities, available experience with
CXCR4-directed diagnostics and endoradiotherapy mainly focuses on hematologic …

In vivo targeting of CXCR4—new horizons

M Schottelius, K Herrmann, C Lapa - Cancers, 2021 - mdpi.com
Simple Summary Beyond its pre-eminent role in the context of tumor cell growth as well as
metastasis, the CXC motif chemokine receptor 4 (CXCR4) is a key player in the …

[HTML][HTML] The theranostic promise for Neuroendocrine Tumors in the late 2010s-Where do we stand, where do we go?

RA Werner, A Weich, M Kircher, LB Solnes… - Theranostics, 2018 - ncbi.nlm.nih.gov
More than 25 years after the first peptide receptor radionuclide therapy (PRRT), the concept
of somatostatin receptor (SSTR)-directed imaging and therapy for neuroendocrine tumors …

[HTML][HTML] A new class of PentixaFor-and PentixaTher-based theranostic agents with enhanced CXCR4-targeting efficiency

T Osl, A Schmidt, M Schwaiger, M Schottelius… - Theranostics, 2020 - ncbi.nlm.nih.gov
Non-invasive PET imaging of CXCR4 expression in cancer and inflammation as well as
CXCR4-targeted radioligand therapy (RLT) have recently found their way into clinical …

Theranostics: leveraging molecular imaging and therapy to impact patient management and secure the future of nuclear medicine

LB Solnes, RA Werner, KM Jones… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Nuclear medicine is experiencing a renaissance, with US Food and Drug Administration
approval recently being obtained for theranostic agents and a wide variety of such agents …

Radionuclide imaging and therapy directed towards the tumor microenvironment: A multi-cancer approach for personalized medicine

CD van der Heide, SU Dalm - European Journal of Nuclear Medicine and …, 2022 - Springer
Targeted radionuclide theranostics is becoming more and more prominent in clinical
oncology. Currently, most nuclear medicine compounds researched for cancer theranostics …