Progression of radio-labeled molecular imaging probes targeting chemokine receptors

H Yi, L Qin, X Ye, J Song, J Ji, T Ye, J Li, L Li - Critical Reviews in Oncology …, 2024 - Elsevier
Chemokine receptors are significantly expressed in the surface of most inflammatory cells
and tumor cells. Guided by chemokines, inflammatory cells which express the relevant …

Exploring innovative strides in radiolabeled nanoparticle progress for multimodality cancer imaging and theranostic applications

A Najdian, D Beiki, M Abbasi, A Gholamrezanezhad… - Cancer Imaging, 2024 - Springer
Multimodal imaging unfolds as an innovative approach that synergistically employs a
spectrum of imaging techniques either simultaneously or sequentially. The integration of …

Novel peptide-based PET probe for non-invasive imaging of CXC chemokine receptor type 4 (CXCR4) in tumors

AM Trotta, M Aurilio, C D'Alterio, C Ierano… - Journal of Medicinal …, 2021 - ACS Publications
The recently reported CXCR4 antagonist 3 (Ac-Arg-Ala-[DCys-Arg-2Nal-His-Pen]-CO2H)
was investigated as a molecular scaffold for a CXCR4-targeted positron emission …

[HTML][HTML] Evaluation of somatostatin and CXCR4 receptor expression in a large set of prostate cancer samples using tissue microarrays and well-characterized …

C Werner, O Dirsch, U Dahmen, MO Grimm… - Translational …, 2020 - Elsevier
BACKGROUND: Prostate cancer (PCa) is the most common type of cancer among men in
Western countries. Despite numerous therapeutic options, few treatments are available for …

Discovery of novel CXCR4 inhibitors for the treatment of inflammation by virtual screening and biological evaluation

F Wang, J Ma, L Yang, P Hu, S Tang, J Wang… - European Journal of …, 2024 - Elsevier
CXC chemokine receptor type 4 (CXCR4) exerts considerable influence on the
pathogenesis of inflammatory disorders and offers a potent avenue for drug intervention …

Somatostatin and chemokine CXCR4 receptor expression in pancreatic adenocarcinoma relative to pancreatic neuroendocrine tumours

Y Kajtazi, D Kaemmerer, J Sänger, S Schulz… - Journal of Cancer …, 2019 - Springer
Purpose Pancreatic adenocarcinoma (PAC) represents one of the most fatal types of cancer
with an exceptionally poor prognosis, underscoring the need for improved diagnostic and …

Simultaneous PET/MRI: The future gold standard for characterizing motor neuron disease—A clinico-radiological and neuroscientific perspective

FD Juengling, F Wuest, S Kalra, F Agosta… - Frontiers in …, 2022 - frontiersin.org
Neuroimaging assessment of motor neuron disease has turned into a cornerstone of its
clinical workup. Amyotrophic lateral sclerosis (ALS), as a paradigmatic motor neuron …

Development of CXCR4 modulators based on the lead compound RB-108

R Bai, X Jie, J Sun, Z Liang, Y Yoon, A Feng… - European journal of …, 2019 - Elsevier
The CXCR4/CXCL12 axis plays prominent roles in tumor metastasis and inflammation.
CXCR4 has been shown to be involved in a variety of inflammation-related diseases …

Expression of chemokine receptor CXCR4 in tumor cells and content of CXCL12+-fibroblasts in endometrioid carcinoma of endometrium

LG Buchynska, OM Movchan… - Experimental …, 2021 - exp-oncology.com.ua
Background: The expression of the CXCL12 chemokine and its receptor CXCR4 in the
stromal component of the tumor plays an important role in tumor cell migration, proliferation …

[图书][B] Handbook of radiopharmaceuticals: methodology and applications

MR Kilbourn, PJH Scott - 2021 - books.google.com
Sorgfältig aktualisierte Neuauflage dieses wegweisenden Referenzwerk der
radiopharmazeutischen Wissenschaften Die 2. Auflage des Handbook of …